Acquired and intrinsic gemcitabine resistance in pancreatic cancer therapy: Environmental factors, molecular profile and drug/nanotherapeutic approaches
A high number of cancer patients around the world rely on gemcitabine (GEM) for
chemotherapy. During local metastasis of cancers, surgery is beneficial for therapy, but …
chemotherapy. During local metastasis of cancers, surgery is beneficial for therapy, but …
Hallmarks of pancreatic cancer: spotlight on TAM receptors
N Vázquez-Bellón, N Martínez-Bosch, PG de Frutos… - …, 2024 - thelancet.com
Pancreatic ductal adenocarcinoma (PDAC) represents the most prevalent type of pancreatic
cancer and ranks among the most aggressive tumours, with a 5-year survival rate of less …
cancer and ranks among the most aggressive tumours, with a 5-year survival rate of less …
Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinoma
Poor outcomes and chemotherapy resistance for patients with pancreatic adenocarcinoma
(PAAD) are a challenge worldwide, and new or improved prognostic biomarkers are …
(PAAD) are a challenge worldwide, and new or improved prognostic biomarkers are …
Oncogenic Roles of Laminin Subunit Gamma‐2 in Intrahepatic Cholangiocarcinoma via Promoting EGFR Translation
J Zhang, F Ji, Y Tan, L Zhao, Y Zhao, J Liu… - Advanced …, 2024 - Wiley Online Library
Intrahepatic cholangiocarcinoma (iCCA) is a highly lethal biliary epithelial cancer in the liver.
Here, Laminin subunit gamma‐2 (LAMC2) with important oncogenic roles in iCCA is …
Here, Laminin subunit gamma‐2 (LAMC2) with important oncogenic roles in iCCA is …
The Interaction of LAMA2 and Duration of Illness Affects the Thickness of the Right Transverse Temporal Gyrus in Major Depressive Disorder
G Chen, L Li, T Sun, C Jiang, W Xu… - Neuropsychiatric …, 2023 - Taylor & Francis
Background Depression is a heritable brain disorder. Laminin genes were recently identified
to affect the brain's overall thickness through neurogenesis, differentiation, and migration in …
to affect the brain's overall thickness through neurogenesis, differentiation, and migration in …
LAMC2 regulates the proliferation, invasion, and metastasis of gastric cancer via PI3K/Akt signaling pathway
L Cheng, X Li, W Dong, J Yang, P Li, X Qiang… - Journal of Cancer …, 2024 - Springer
Objectives Gastric cancer (GC) is a prevalent malignant tumor widely distributed globally,
exhibiting elevated incidence and fatality rates. The gene LAMC2 encodes the laminin …
exhibiting elevated incidence and fatality rates. The gene LAMC2 encodes the laminin …
LncRNAs-Regulated High Expression of LAMC2 Reveals a Prognostic and Immunological Value in Pancreatic Adenocarcinoma
J Liu, M Wang, M Wang, F Wang, B Zhang - Biochemical Genetics, 2024 - Springer
Pancreatic adenocarcinoma (PAAD) is one of the most hazardous cancers in digestive
system, and the prognosis is notoriously bad. Increasing evidences indicate that Laminin …
system, and the prognosis is notoriously bad. Increasing evidences indicate that Laminin …