Gene therapy for inherited hearing loss: updates and remaining challenges
R Hahn, KB Avraham - Audiology Research, 2023 - mdpi.com
Hearing loss stands as the most prevalent sensory deficit among humans, posing a
significant global health challenge. Projections indicate that by 2050, approximately 10% of …
significant global health challenge. Projections indicate that by 2050, approximately 10% of …
Advances in cochlear gene therapies
MJ Klimara, RJH Smith - Current opinion in pediatrics, 2023 - journals.lww.com
Gene therapies for hearing loss are expected to enter clinical trials in the immediate future.
To provide referral for appropriate trials and counseling regarding benefits of genetic …
To provide referral for appropriate trials and counseling regarding benefits of genetic …
Recovery kinetics of dual AAV-mediated human otoferlin expression
JB Sellon, KS So, A D'Arcangelo… - Frontiers in Molecular …, 2024 - frontiersin.org
Deafness-causing deficiencies in otoferlin (OTOF) have been addressed preclinically using
dual adeno-associated virus (AAV)-based approaches. However, timing of transduction …
dual adeno-associated virus (AAV)-based approaches. However, timing of transduction …
Gene Therapy for Inherited Hearing Loss: Updates and Chal-lenges
R Hahn, KB Avraham - 2023 - preprints.org
Hearing loss stands as the most prevalent sensory deficit among humans, posing a
significant global health challenge. Projections indicate that by 2050, approximately 10% of …
significant global health challenge. Projections indicate that by 2050, approximately 10% of …