Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems
Efficient gene therapy is mainly dependent on the gene transfer capability of gene delivery
vectors. Non-viral vectors have become the research interest of many researchers because …
vectors. Non-viral vectors have become the research interest of many researchers because …
Imaging preclinical tumour models: improving translational power
M De Jong, J Essers, WM Van Weerden - Nature Reviews Cancer, 2014 - nature.com
Recent developments and improvements of multimodal imaging methods for use in animal
research have substantially strengthened the options of in vivo visualization of cancer …
research have substantially strengthened the options of in vivo visualization of cancer …
[HTML][HTML] The role of the helper lipid on the DNA transfection efficiency of lipopolyplex formulations
Multifunctional, lipopolyplex formulations comprising a mixture of cationic liposomes and
cationic, receptor-targeting peptides have potential use in gene therapy applications …
cationic, receptor-targeting peptides have potential use in gene therapy applications …
Gadolinium-based nanoscale MRI contrast agents for tumor imaging
Gadolinium-based nanoscale magnetic resonance imaging (MRI) contrast agents (CAs)
have gained significant momentum as a promising nanoplatform for detecting tumor tissue in …
have gained significant momentum as a promising nanoplatform for detecting tumor tissue in …
The effect of Cryoprotectants and storage conditions on the transfection efficiency, stability, and safety of lipid‐based nanoparticles for mRNA and DNA delivery
KN Kafetzis, N Papalamprou, E McNulty… - Advanced …, 2023 - Wiley Online Library
Lipid‐based nanoparticles have recently shown great promise, establishing themselves as
the gold standard in delivering novel RNA therapeutics. However, research on the effects of …
the gold standard in delivering novel RNA therapeutics. However, research on the effects of …
Assembly strategy of liposome and polymer systems for siRNA delivery
H Song, SL Hart, Z Du - International journal of pharmaceutics, 2021 - Elsevier
In recent years, gene therapy has made tremendous progress in the development of disease
treatment. Among them, siRNA offers specificity of gene silencing, ease of synthesis, and …
treatment. Among them, siRNA offers specificity of gene silencing, ease of synthesis, and …
Strategies and materials of" SMART" non-viral vectors: Overcoming the barriers for brain gene therapy
Y Li, L Liu, W Ji, H Peng, R Zhao, X Zhang - Nano Today, 2020 - Elsevier
Most brain diseases such as tumors and neurodegenerative diseases are devastating for
patients with high morbidity and mortality. Gene therapy is a promising strategy for the …
patients with high morbidity and mortality. Gene therapy is a promising strategy for the …
Redoxable heteronanocrystals functioning magnetic relaxation switch for activatable T1 and T2 dual-mode magnetic resonance imaging
MH Kim, HY Son, GY Kim, K Park, YM Huh, S Haam - Biomaterials, 2016 - Elsevier
Abstract T 1/T 2 dual-mode magnetic resonance (MR) contrast agents (DMCAs) have gained
much attention because of their ability to improve accuracy by providing two pieces of …
much attention because of their ability to improve accuracy by providing two pieces of …
Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis
There is increasing evidence that the Myocardin-related transcription factor/Serum response
factor (MRTF/SRF) pathway plays a key role in fibroblast activation and that knocking down …
factor (MRTF/SRF) pathway plays a key role in fibroblast activation and that knocking down …