Dementia is a permanent illness characterized by mental instability, memory loss, and
cognitive decline. Many studies have demonstrated an association between diabetes and …

Neurodegenerative disorders are accompanied by neuronal degeneration and glial
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …

The comprehensive anabolic effects of insulin throughout the body, in addition to the control
of glycemia, include ensuring lipid homeostasis and anti-inflammatory modulation …

Intermittent hypoxia (IH), one of the primary pathologies of sleep apnea syndrome (SAS),
exposes cells throughout the body to repeated cycles of hypoxia/normoxia that result in …

A decrease in the activity of the insulin signaling system of the brain, due to both central
insulin resistance and insulin deficiency, leads to neurodegeneration and impaired …

Introduction Type 2 diabetes (T2D) is a multifactorial disease involving genetic and
environmental components. Several genome-wide association studies (GWAS) have been …

Cognitive impairment and malnutrition are prevalent in patients on hemodialysis (HD), and
they negatively affect the outcomes of HD patients. Evidence suggests that cognitive …

Abstract Aims/Introduction This study was carried out to investigate the relationship of
stressful life events (SLEs) with the risk of cognitive impairment in patients with type 2 …

Literature data on epidemiology, mechanisms of development, features of the course of
cognitive disorders in type 2 diabetes mellitus (T2DM), as well as prospects for their …

Cognitive deficit is one of the challenging complications of type 2 diabetes. Sphingosine 1-
phosphate receptors (S1PRs) have been implicated in various neurodegenerative and …