Intercellular calcium (Ca2+) waves (ICWs) represent the propagation of increases in
intracellular Ca2+ through a syncytium of cells and appear to be a fundamental mechanism …

Large conductance, Ca 2+-activated potassium (BK) channels are widely expressed
throughout the animal kingdom and play important roles in many physiological processes …

Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known
members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand …

Cochlear endolymph, an extracellular solution containing 150 mM K+, exhibits a positive
potential of+ 80 mV. This is called the endocochlear potential (EP) and is essential for …

Strial melanocytes are required for normal development and correct functioning of the
cochlea. Hearing deficits have been reported in albino individuals from different species …

The vertebrate inner ear, responsible for hearing and balance, is able to sense minute
mechanical stimuli originating from an extraordinarily broad range of sound frequencies and …

Despite recent advances, a better understanding of the complexity of gap-junctional
communication in the inner ear and the structure–function relationships of connexin proteins …

The tight regulation of Ca2+ is essential for inner ear function, and yet the role of Ca2+
binding proteins (CaBPs) remains elusive. By using immunofluorescence and reverse …

Abstract Connexin 26 (Cx26) and connexin 30 (Cx30) form hemichannels that release ATP
from the endolymphatic surface of cochlear supporting and epithelial cells and also form gap …

Cadherins form a large family of proteins often involved in calcium-dependent cellular
adhesion. Although classical members of the family can provide a physical bond between …