Biological role and related natural products of SIRT1 in nonalcoholic fatty liver

D Meng, F Zhang, W Yu, X Zhang, G Yin… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Non-alcoholic fatty liver disease (NAFLD) is an umbrella term for a range of diseases
ranging from hepatic fat accumulation and steatosis to non-alcoholic steatohepatitis (NASH) …

Montelukast prevents mice against carbon tetrachloride-and methionine-choline deficient diet-induced liver fibrosis: Reducing hepatic stellate cell activation and …

S Pu, J Zhang, C Ren, H Zhou, Y Wang, Y Wu, S Yang… - Life Sciences, 2023 - Elsevier
Aims Montelukast is an antagonist of cysteinyl leukotriene receptor 1 (CysLTR1) that
protects against inflammation and oxidative stress. However, the function of montelukast in …

[HTML][HTML] Exploring the effectiveness of flavone derivatives for treating liver diseases: Utilizing DFT, molecular docking, and molecular dynamics techniques

ST Quayum, NJI Esha, S Siraji, SS Al Abbad… - MethodsX, 2024 - Elsevier
In exploring nature's potential in addressing liver-related conditions, this study investigates
the therapeutic capabilities of flavonoids. Utilizing in silico methodologies, we focus on …

[HTML][HTML] Silibinin Prevents TGFβ-Induced EMT of RPE in Proliferative Vitreoretinopathy by Inhibiting Stat3 and Smad3 Phosphorylation

X Ma, Y Xie, Y Gong, C Hu, K Qiu… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: The purpose of this study was to investigate the effects of silibinin on epithelial-
mesenchymal transition (EMT) of retinal pigment epithelial (RPE) and proliferative …