Mycobacterium tuberculosis (Mtb) is known to evade host immune responses and persist in
macrophages for long periods. A mechanism that the host uses to combat Mtb is xenophagy …

Survival of the live attenuated Bacillus Calmette-Guérin (BCG) vaccine amidst harsh host
environments is key for BCG effectiveness as it allows continuous immune response …

Autophagy is a crucial immune defense mechanism that controls the survival and
pathogenesis of M. tb by maintaining cell physiology during stress and pathogen attack. The …

MHC class I antigen processing is an underappreciated area of nonviral host–pathogen
interactions, bridging both immunology and cell biology, where the pathogen's natural life …

Infections are known to cause tumours though more attributed to viruses. Strong
epidemiological links suggest association between bacterial infections and cancers as …

Tuberculosis (TB) remains one of the most afflictive bacterial infections globally. In high
burden TB countries, surveillance, diagnosis and treatment of drug resistant TB (RR and …

Multigene PE/PPE family is exclusively present in mycobacterium species. Only few selected
genes of this family have been characterized till date. Rv3539 was annotated as PPE63 with …

Through comparative analyses using BLASTp and BLASTn of the 25 target sequences, our
research identified two unique post-transcriptional modifiers, Rv1509 and Rv2231A, which …

The impact of artificial intelligence (AI) in understanding biological processes is potentially
immense. Structural elucidation of mycobacterial PE_PGRS is sustenance to unveil the role …

Background: Understanding the protein's subcellular localization and secretory nature can
greatly improve the target identification for diagnostic assays and drug discovery, although …