RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Aptamer-based targeted delivery of functional nucleic acids
S Xie, W Sun, T Fu, X Liu, P Chen, L Qiu… - Journal of the …, 2023 - ACS Publications
Functional nucleic acid (NA)-based drugs have a broad range of applications since they
allow the alteration and control of gene/protein expression patterns in cells. In principle …
allow the alteration and control of gene/protein expression patterns in cells. In principle …
Temperature-sensitive lipid-coated carbon nanotubes for synergistic photothermal therapy and gene therapy
Y Zhao, T Zhao, Y Cao, J Sun, Q Zhou, H Chen… - ACS …, 2021 - ACS Publications
The combination of photothermal therapy (PTT) and gene therapy (GT) shows great
potential to achieve synergistic anti-tumor activity. However, the lack of a controlled release …
potential to achieve synergistic anti-tumor activity. However, the lack of a controlled release …
[HTML][HTML] Engineered exosomes from different sources for cancer-targeted therapy
M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
Breast cancer: conventional diagnosis and treatment modalities and recent patents and technologies
MI Nounou, F ElAmrawy, N Ahmed… - Breast cancer: basic …, 2015 - journals.sagepub.com
Breast cancer is the most prevalent cancer among women worldwide. However, increased
survival is due to the dramatic advances in the screening methods, early diagnosis, and …
survival is due to the dramatic advances in the screening methods, early diagnosis, and …
[HTML][HTML] Nano-based delivery of RNAi in cancer therapy
Y Xin, M Huang, WW Guo, Q Huang, L Zhang, G Jiang - Molecular cancer, 2017 - Springer
Background RNA interference (RNAi), a newly developed method in which RNA molecules
inhibit gene expression, has recently received considerable research attention. In the …
inhibit gene expression, has recently received considerable research attention. In the …
Cyclodextrin based natural nanostructured carbohydrate polymers as effective non-viral siRNA delivery systems for cancer gene therapy
H Mousazadeh, Y Pilehvar-Soltanahmadi… - Journal of controlled …, 2021 - Elsevier
Short interfering RNAs (siRNAs), as small non-coding RNA fragments, are one of the widely
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …
Carbon nanotubes as an emerging nanocarrier for the delivery of doxorubicin for improved chemotherapy
Carbon nanotubes (CNTs), a versatile nanocarrier for doxorubicin (DOX) delivery had
attracted significant attention in drug delivery of pharmaceuticals. Several properties such as …
attracted significant attention in drug delivery of pharmaceuticals. Several properties such as …
Carbon nanotubes as cancer therapeutic carriers and mediators
Carbon nanotubes (CNTs) have received increasing attention in biomedical fields because
of their unique structures and properties, including high aspect ratios, large surface areas …
of their unique structures and properties, including high aspect ratios, large surface areas …
[HTML][HTML] Aptamer grafted nanoparticle as targeted therapeutic tool for the treatment of breast cancer
A Sheikh, S Md, P Kesharwani - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Breast carcinomas repeat their number and grow exponentially making it extremely frequent
malignancy among women. Approximately, 70–80% of early diagnosed or non-metastatic …
malignancy among women. Approximately, 70–80% of early diagnosed or non-metastatic …