Diagnosis and management of toxicities of immune checkpoint inhibitors in hepatocellular carcinoma
Immune checkpoint inhibitors (ICIs) have reshaped cancer therapy. ICIs enhance T cell
activation through various mechanisms and may help reverse the exhausted phenotype of …
activation through various mechanisms and may help reverse the exhausted phenotype of …
Extrahepatic manifestations of chronic hepatitis C virus infection
P Cacoub, C Comarmond, F Domont… - Therapeutic …, 2016 - journals.sagepub.com
During hepatitis C virus (HCV) chronic infection, extrahepatic manifestations are frequent
and polymorphous. This article reports on a large cohort of patients with HCV-related …
and polymorphous. This article reports on a large cohort of patients with HCV-related …
EASL recommendations on treatment of hepatitis C: final update of the series☆
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …
EASL recommendations on treatment of hepatitis C 2018
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …
Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis
D Saadoun, M Rosenzwajg, F Joly, A Six… - … England Journal of …, 2011 - Mass Medical Soc
Background Patients with vasculitis induced by the hepatitis C virus (HCV) have reduced
levels of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of …
levels of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of …
Cryoglobulinaemia
D Roccatello, D Saadoun, M Ramos-Casals… - Nature Reviews …, 2018 - nature.com
Cryoglobulinaemia refers to the serum presence of cryoglobulins, which are defined as
immunoglobulins that precipitate at temperatures< 37° C. Type I cryoglobulinaemia consists …
immunoglobulins that precipitate at temperatures< 37° C. Type I cryoglobulinaemia consists …
Cryoglobulinemia vasculitis
P Cacoub, C Comarmond, F Domont, L Savey… - The American journal of …, 2015 - Elsevier
Cryoglobulinemic vasculitis (CryoVas) is a small-vessel vasculitis involving mainly the skin,
the joints, the peripheral nervous system, and the kidneys. Type I CryoVas is single …
the joints, the peripheral nervous system, and the kidneys. Type I CryoVas is single …
Extrahepatic manifestations of chronic HCV infection
Extrahepatic Manifestations of Chronic HCV Infection Hepatitis C virus infection is
associated with nonhepatic diseases, including mixed cryoglobulinemic vasculitis, B-cell …
associated with nonhepatic diseases, including mixed cryoglobulinemic vasculitis, B-cell …
Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
M Rosenzwajg, G Churlaud, R Mallone, A Six… - Journal of …, 2015 - Elsevier
Most autoimmune diseases (AID) are linked to an imbalance between autoreactive effector T
cells (Teffs) and regulatory T cells (Tregs). While blocking Teffs with immunosuppression …
cells (Teffs) and regulatory T cells (Tregs). While blocking Teffs with immunosuppression …
Viral hepatitis C
Epidemiology Chronic hepatitis C virus infection is a major cause of chronic liver disease
and death throughout the world. 1, 2, 4–9 Very effective treatment is now available, which …
and death throughout the world. 1, 2, 4–9 Very effective treatment is now available, which …