Recently, significant advances in modern medicine and therapeutic agents have been
achieved. However, the search for effective antidiabetic drugs is continuous and …

The global epidemic of diabetes has brought heavy pressure on public health. New effective
anti-diabetes strategies are urgently needed. Trigonelline is the main component of …

The main objective of this experiment was to determine the effects of yogurt supplementation
on fat deposition, oxidative stress, inflammation and fibrosis in the liver of rats with high-fat …

Long-term consumption of a Western diet is a major cause of type 2 diabetes mellitus
(T2DM). However, the effects of diet on pancreatic structure and function remain unclear …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most common
phenotype of dementia. Trigonelline is an alkaloid found in medicinal plants such as …

The development of obesity-associated complications is related to various pathogenic
events including chronic inflammation, oxidative stress and generation of advanced …

Brain inflammation is associated with cognitive dysfunction, especially in elderly.
Trigonelline is a plant alkaloid and a major component of coffee and fenugreek with anti …

Trigonelline has been reported to serve an important role in cell cycle control, oxidative and
ultraviolet stress and DNA methylation. In the present study, the effects of trigonelline were …

The prevalence of obesity has risen in the last decades, and it has caused massive health
burdens on people's health, especially metabolic and cardiovascular issues. The risk of …

Background: Accumulating experimental data supports the capacity of natural compounds to
intervene in complicated molecular pathways underlying the pathogenesis of certain human …