Intracellular innate immune surveillance devices in plants and animals

JDG Jones, RE Vance, JL Dangl - Science, 2016 - science.org
BACKGROUND Pathogens cause agricultural devastation and huge economic losses. Up to
30% of our crops are lost before or after harvest to pathogens and pests, wasting water and …

Help wanted: helper NLRs and plant immune responses

LM Jubic, S Saile, OJ Furzer, F El Kasmi… - Current opinion in plant …, 2019 - Elsevier
Highlights•A subset of NLRs form robust networks of helpers underlying the bulk of NLRs
that function as sensors.•Ancient, conserved RNL helper NLRs are required for some sensor …

A comparative overview of the intracellular guardians of plants and animals: NLRs in innate immunity and beyond

Z Duxbury, C Wu, P Ding - Annual review of plant biology, 2021 - annualreviews.org
Nucleotide-binding domain leucine-rich repeat receptors (NLRs) play important roles in the
innate immune systems of both plants and animals. Recent breakthroughs in NLR …

Evolutionary convergence and divergence in NLR function and structure

E Meunier, P Broz - Trends in immunology, 2017 - cell.com
The recognition of cellular damage caused by either pathogens or abiotic stress is essential
for host defense in all forms of life in the plant and animal kingdoms. The NOD-like receptors …

Fungal gasdermin-like proteins are controlled by proteolytic cleavage

C Clavé, W Dyrka, EA Turcotte… - Proceedings of the …, 2022 - National Acad Sciences
Gasdermins are a family of pore-forming proteins controlling an inflammatory cell death
reaction in the mammalian immune system. The pore-forming ability of the gasdermin …

Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis

A Daskalov, B Habenstein, R Sabaté… - Proceedings of the …, 2016 - National Acad Sciences
Recent findings have revealed the role of prion-like mechanisms in the control of host
defense and programmed cell death cascades. In fungi, HET-S, a cell death-inducing …

Regulated forms of cell death in fungi

AP Gonçalves, J Heller, A Daskalov, A Videira… - Frontiers in …, 2017 - frontiersin.org
Cell death occurs in all domains of life. While some cells die in an uncontrolled way due to
exposure to external cues, other cells die in a regulated manner as part of a genetically …

Structural insights into the plant immune receptors PRRs and NLRs

J Wang, J Chai - Plant physiology, 2020 - academic.oup.com
Structural Insights into the Plant Immune Receptors PRRs and NLRs1 [OPEN] | Plant
Physiology | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

RPW8/HR repeats control NLR activation in Arabidopsis thaliana

CA Barragan, R Wu, ST Kim, W Xi, A Habring… - PLoS …, 2019 - journals.plos.org
In many plant species, conflicts between divergent elements of the immune system,
especially nucleotide-binding oligomerization domain-like receptors (NLR), can lead to …

3D structure determination of amyloid fibrils using solid-state NMR spectroscopy

A Loquet, N El Mammeri, J Stanek, M Berbon… - Methods, 2018 - Elsevier
The amyloid fold is structurally characterized by a typical cross-β architecture, which is under
debate to represent an energy-favourable folding state that many globular or natively …