Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer

MK Bakht, H Beltran - Nature Reviews Urology, 2024 - nature.com
Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker
and therapeutic target in prostate cancer. The PSMA-targeted theranostic 177Lu-PSMA-617 …

Application of next-generation imaging in biochemically recurrent prostate cancer

JW Moul, ND Shore, KJ Pienta, J Czernin… - Prostate Cancer and …, 2024 - nature.com
Background Biochemical recurrence (BCR) following primary interventional treatment
occurs in approximately one-third of patients with prostate cancer (PCa). Next-generation …

Novel Methods to Assess Tumor Burden and Minimal Residual Disease in Genitourinary Cancers

PC Barata, KK Zarrabi, A Bex, P Grivas, K Hermann… - European urology, 2024 - Elsevier
Background and objective Advances in molecular diagnostics have ushered in a new era for
patients with prostate, renal, and urothelial cancers, with novel radiographic and molecular …

2022 年度前列腺癌基础研究及临床诊疗新进展

潘剑, 朱耀, 戴波, 叶定伟 - 中国癌症杂志, 2023 - china-oncology.com
中国初诊的前列腺癌患者中40%~ 70% 已处于转移性疾病阶段, 而前列腺癌发生,
发展的时空异质性及独特的转移模式使得基于活检组织取材分析免疫标志物的方式困难重重 …

Recent pre-clinical advancements in nuclear medicine: pioneering the path to a limitless future

W Echavidre, D Fagret, M Faraggi, V Picco… - Cancers, 2023 - mdpi.com
Simple Summary This review summarizes recent advances in the nuclear medicine
theranostic approach. It covers the repurposing of historical radiotracers for new indications …

How to report PSMA PET

M Swiha, N Ayati, DE Oprea-Lager, F Ceci… - Seminars in Nuclear …, 2024 - Elsevier
Prostate cancer (PCa) is the most common cancer diagnosed in men in most developed
countries and a leading cause of cancer-related morbidity and mortality. Prostate-specific …

The role of mpMRI in the assessment of prostate cancer recurrence using the PI-RR system: diagnostic accuracy and interobserver agreement in readers with different …

C Bergaglio, V Giasotto, M Marcenaro, S Barra… - Diagnostics, 2023 - mdpi.com
Background: treated prostate cancer (PCa) patients develop biochemical recurrence (BCR)
in 27–53% of cases; the role of MRI in this setting is still controversial. In 2021 a panel of …

Radiopharmaceuticals and their applications in medicine

S Zhang, X Wang, X Gao, X Chen, L Li, G Li… - … and Targeted Therapy, 2025 - nature.com
Radiopharmaceuticals involve the local delivery of radionuclides to targeted lesions for the
diagnosis and treatment of multiple diseases. Radiopharmaceutical therapy, which directly …

[68Ga]PSMA-11 for positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA)-positive lesions in men with prostate cancer

J Clore, PJH Scott - Expert Review of Molecular Diagnostics, 2024 - Taylor & Francis
Introduction Theranostics targeting prostate-specific membrane antigen (PSMA) represent a
new targeted approach for prostate cancer care that combines diagnostic and therapeutic …

Implementing evidence‐based strategies for men with biochemically recurrent and advanced prostate cancer: Consensus recommendations from the US Prostate …

AH Bryce, N Agarwal, H Beltran, MH Hussain… - Cancer, 2025 - Wiley Online Library
Current US clinical practice guidelines for advanced prostate cancer management contain
recommendations based on high‐level evidence from randomized controlled trials; …