Inactivated and live attenuated vaccines have improved human life and significantly reduced
morbidity and mortality of several human infectious diseases. However, these vaccines have …

The WHO recently proposed an updated nomenclature for mumps virus (MuV). WHO
currently recognizes 12 genotypes of MuV, assigned letters from A to N (excluding E and M) …

Negative-stranded RNA viruses (NSVs) are important human pathogens, including
emerging and reemerging viruses that cause respiratory, hemorrhagic and other severe …

The clinical picture of mumps was first described by Hippocrates in the fifth century BC in his
first book of Epidemics, in which he described outbreaks among young males characterized …

An outbreak of mumps within a student population in Scotland was investigated to assess
the effect of previous vaccination on infection and clinical presentation, and any genotypic …

Mumps outbreaks among vaccinated patients have become increasingly common in recent
years. While there are multiple conditions driving this re-emergence, convention has …

A recent resurgence of mumps in doubly vaccinated cohorts has been observed, identifying
genotype G as the current predominant genotype. In this study, the neutralization efficacy of …

The resurgence of mumps in vaccinated adult populations has raised concerns about
possible waning vaccine immunity or a potential lack of protection to the circulating strain. A …

The two most commonly used methods for the determination of a virus potency are plaque
assay and 50% cell culture infective dose (CCID50) assay, both based on cytopathic effect …

Resurgent mumps outbreaks have raised questions about the current efficacy of mumps
vaccines. We have applied immunoinformatics techniques based on principal component …