Introduction The resistance to chemotherapy is a significant hurdle in breast cancer
treatment, prompting the exploration of innovative strategies. This review discusses the …

The gut microbiota present in the human digestive system is incredibly varied and is home to
trillions of microorganisms. The gut microbiome is shaped at birth, while numerous genetic …

Purpose Existing prognostic biomarkers are inadequate for stratifying breast cancer patients
with the highest risk of tumor progression at the time of diagnosis. Here, we demonstrate that …

Cancer of the breast is the mainly prevalent class of cancer in females diagnosed over the
globe. It also happens to be the 2nd most prevalent reason of cancer-related deaths among …

Background The molecular diversity exhibited by diffuse large B-cell lymphoma (DLBCL) is
a significant obstacle facing current precision therapies. However, scoring using the …

Aim: To investigate the therapeutic potential of mebendazole (MBZ)-loaded nanostructured
lipid carriers (NLCs). Methodology: NLC-MBZ was prepared and characterized to evaluate …

Introduction Guanine nucleotide exchange factors (GEFs) regulate the activation of small
GTPases (G proteins) of the Ras superfamily proteins controlling cellular functions. Ras …

Background: Breast cancer is the leading cause of frequent malignancy and morbidity
among women across the globe, with an increment of 0.5% incidences every year. The …

The nuclear envelope (NE) is a critical component in maintaining the function and structure
of the eukaryotic nucleus. The NE and lamina are disassembled during each cell cycle to …

Simple Summary This research revealed that the downregulation of fumarate hydratase in
patients is associated with poor prognosis. Mechanistically, FH binds to RAN, which inhibits …