Xenodiagnosis to address key questions in visceral leishmaniasis control and elimination

OP Singh, E Hasker, M Boelaert, D Sacks… - PLOS Neglected …, 2020 - journals.plos.org
Visceral leishmaniasis (VL) remains an important public health issue worldwide causing
substantial morbidity and mortality. The Indian subcontinent accounted for up to 90% of the …

Human genetics of leishmania infections

JM Blackwell, M Fakiola, LC Castellucci - Human genetics, 2020 - Springer
Identifying genetic risk factors for parasitic infections such as the leishmaniases could
provide important leads for improved therapies and vaccines. Until recently most genetic …

Inferring transmission trees to guide targeting of interventions against visceral leishmaniasis and post–kala-azar dermal leishmaniasis

LAC Chapman, SEF Spencer… - Proceedings of the …, 2020 - National Acad Sciences
Understanding of spatiotemporal transmission of infectious diseases has improved
significantly in recent years. Advances in Bayesian inference methods for individual-level …

Indoor residual spraying for the control of visceral leishmaniasis: A systematic review

C Faber, C Montenegro Quiñonez… - PLoS Neglected …, 2022 - journals.plos.org
Indoor Residual Spraying (IRS) is one of the interventions to control the vectors of Visceral
Leishmaniasis (VL). Different insecticides are used in affected countries, also in the …

Visceral leishmaniasis outbreaks in Bihar: community-level investigations in the context of elimination of kala-azar as a public health problem

K Priyamvada, J Bindroo, MP Sharma, LAC Chapman… - Parasites & vectors, 2021 - Springer
Background With visceral leishmaniasis (VL) incidence at its lowest level since the 1960s,
increasing attention has turned to early detection and investigation of outbreaks. Methods …

Post kala azar dermal leishmaniasis and leprosy prevalence and distribution in the Muzaffarpur health and demographic surveillance site

E Hasker, P Malaviya, VK Scholar… - PLoS neglected …, 2019 - journals.plos.org
Introduction Post-kala-azar dermal leishmaniasis (PKDL) is a skin manifestation that is a late
clinical outcome of visceral leishmaniasis (VL). Its presentation is similar to leprosy, and the …

Less is more: Developing an approach for assessing clustering at the lower administrative boundaries that increases the yield of active screening for leprosy in Bihar …

N Ortuño-Gutiérrez, PW Shih, A Wagh… - PLoS Neglected …, 2022 - journals.plos.org
Background In India, leprosy clusters at hamlet level but detailed information is lacking. We
aim to identify high-incidence hamlets to be targeted for active screening and post-exposure …

A model of vector-targeted interventions for visceral leishmaniasis

C Petersen - The Lancet Infectious Diseases, 2024 - thelancet.com
Luc Coffeng and colleagues analysed how reductions in the abundance of the sandfly
Phlebotomus argentipes as a result of targeted indoor residual spraying (IRS) with the …

[HTML][HTML] Insights from mathematical modelling and quantitative analysis on the proposed WHO 2030 targets for visceral leishmaniasis on the Indian subcontinent

NTDMCVL Group - Gates Open Research, 2019 - ncbi.nlm.nih.gov
Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania
protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is …