What defines a healthy gut microbiome?

M Van Hul, PD Cani, C Petitfils, WM De Vos, H Tilg… - Gut, 2024 - gut.bmj.com
The understanding that changes in microbiome composition can influence chronic human
diseases and the efficiency of therapies has driven efforts to develop microbiota-centred …

A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation

Z Ma, T Zuo, N Frey, AY Rangrez - Signal Transduction and Targeted …, 2024 - nature.com
The human microbiome is a complex and dynamic system that plays important roles in
human health and disease. However, there remain limitations and theoretical gaps in our …

Impacts of COVID-19 pandemic on early life gut microbiome

L Zhang, W Xu, HYH Meng, JYL Ching, Y Liu… - Gut …, 2025 - Taylor & Francis
Increased hygiene and sanitation are theorized to predispose to developing atopic
diseases, a process potentially mediated by the gut microbiome. We hypothesized that the …

A cohort study in family triads: impact of gut microbiota composition and early life exposures on intestinal resistome during the first two years of life

R Jokela, KMM Pärnänen, AJ Ponsero, L Lahti… - Gut …, 2024 - Taylor & Francis
Antibiotic resistance genes (ARGs) are prevalent in the infant gut microbiota and make up
the intestinal resistome, representing a community ARG reservoir. This study focuses on the …

The human gut metacommunity as a conceptual aid in the development of precision medicine

GW Tannock - Frontiers in microbiology, 2024 - frontiersin.org
Human gut microbiomes (microbiotas) are highly individualistic in taxonomic composition
but nevertheless are functionally similar. Thus, collectively, they comprise a …

The case for microbial intervention at weaning

JN Flores, JB Lubin, MA Silverman - Gut Microbes, 2024 - Taylor & Francis
Weaning, the transition from a milk-based diet to solid food, coincides with the most
significant shift in gut microbiome composition in the lifetime of most mammals. Notably, this …

Comparative analysis of the gut microbiota composition and diversity in Erinaceus amurensis from the Wandashan Mountain range area based on metagenomics

X Jia, Q Li, X Yang, D Li, Z Jin - Frontiers in Microbiology, 2024 - frontiersin.org
This study aimed to preliminarily explore the composition and diversity of intestinal bacteria
in Erinaceus amurensis during breeding period, aiding in the field rescue and population …

Enhanced metagenomics-enabled transmission inference with TRACS

G Tonkin-Hill, Y Shao, AE Zarebski, S Mallawaarachchi… - bioRxiv, 2024 - biorxiv.org
Coexisting strains of the same species within the human microbiota pose a substantial
challenge to inferring the host-to-host transmission of both pathogenic and commensal …

From parent to progeny

S Shama, MR Asbury, DL O'Connor - Cell Host & Microbe, 2024 - Elsevier
How infants acquire their gut microbial communities and the various factors influencing
these dynamics remain unclear. In this issue of Cell Host & Microbe, Selma-Royo et al. and …

[HTML][HTML] Host-microbiota interactions in the infant gut revealed by daily faecal sample time series

N van Beek, I Katavisto, M Lehto, KL Kolho… - Microbiome Research …, 2024 - oaepublish.com
Aim: This study aims to explore the interplay between host immune factors and gut
microbiota in human infants in vivo using time-series daily stool samples and identify …