The “mitochondrial stress responses”: The “Dr. Jekyll and Mr. Hyde” of neuronal disorders

S Patergnani, G Morciano, M Carinci… - Neural Regeneration …, 2022 - journals.lww.com
Neuronal disorders are associated with a profound loss of mitochondrial functions caused
by various stress conditions, such as oxidative and metabolic stress, protein folding or import …

Radiation sensitivity in a preclinical mouse model of medulloblastoma relies on the function of the intrinsic apoptotic pathway

AJ Crowther, JK Ocasio, F Fang, J Meidinger, J Wu… - Cancer research, 2016 - AACR
While treatments that induce DNA damage are commonly used as anticancer therapies, the
mechanisms through which DNA damage produces a therapeutic response are …