Host–parasite co-evolution and its genomic signature

D Ebert, PD Fields - Nature Reviews Genetics, 2020 - nature.com
Studies in diverse biological systems have indicated that host–parasite co-evolution is
responsible for the extraordinary genetic diversity seen in some genomic regions, such as …

[HTML][HTML] Advances in the evolutionary understanding of MHC polymorphism

J Radwan, W Babik, J Kaufman, TL Lenz, J Winternitz - Trends in Genetics, 2020 - cell.com
Proteins encoded by the classical major histocompatibility complex (MHC) genes incite the
vertebrate adaptive immune response by presenting peptide antigens on the cell surface …

[图书][B] Parasitology: a conceptual approach

ES Loker, BV Hofkin - 2022 - taylorfrancis.com
Produced amidst the still rippling effects of a pandemic and as the world experiences the
increasing burden of global warming and a rapidly changing biosphere, the second edition …

Spatiotemporal adaptive evolution of an MHC immune gene in a frog-fungus disease system

AL Trujillo, EA Hoffman, CG Becker, AE Savage - Heredity, 2021 - nature.com
Genetic diversity of major histocompatibility complex (MHC) genes is linked to reduced
pathogen susceptibility in amphibians, but few studies also examine broad spatial and …

Long term patterns of association between MHC and helminth burdens in the bank vole support Red Queen dynamics

M Migalska, K Przesmycka, M Alsarraf… - Molecular …, 2022 - Wiley Online Library
Major histocompatibility complex (MHC) genes encode proteins crucial for adaptive
immunity of vertebrates. Negative frequency‐dependent selection (NFDS), resulting from …

What evolutionary processes maintain MHC IIꞵ diversity within and among populations of stickleback?

F Peng, KM Ballare, S Hollis Woodard… - Molecular …, 2021 - Wiley Online Library
Abstract Major Histocompatibility Complex (MHC) genes code for proteins that recognize
foreign protein antigens to initiate T‐cell‐mediated adaptive immune responses. They are …

Host-associated helminth diversity and microbiome composition contribute to anti-pathogen defences in tropical frogs impacted by forest fragmentation

WJ Neely, KMC Souza, RA Martins… - Royal Society …, 2024 - royalsocietypublishing.org
Habitat fragmentation can negatively impact wildlife populations by simplification of
ecological interactions, but little is known about how these impacts extend to host …

Parallel signatures of selection at genomic islands of divergence and the major histocompatibility complex in ecotypes of sockeye salmon across Alaska

WA Larson, TH Dann, MT Limborg… - Molecular …, 2019 - Wiley Online Library
Understanding the genetic mechanisms that facilitate adaptive radiation is an important
component of evolutionary biology. Here, we genotyped 82 neutral SNPs, seven SNPs in …

Balancing selection versus allele and supertype turnover in MHC class II genes in guppies

M Herdegen-Radwan, KP Phillips, W Babik… - Heredity, 2021 - nature.com
Selection pressure from parasites is thought to be a major force shaping the extreme
polymorphism of the major histocompatibility complex (MHC) genes, but the modes and …

Specific MHC class I supertype associated with parasite infection and color morph in a wild lizard population

JD Hacking, D Stuart‐Fox, SS Godfrey… - Ecology and …, 2018 - Wiley Online Library
The major histocompatibility complex (MHC) is a large gene family that plays a central role
in the immune system of all jawed vertebrates. Nonavian reptiles are underrepresented …