Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes

YJ Bae, JM Kim, CH Sohn, JH Choi, BS Choi, YS Song… - Radiology, 2021 - pubs.rsna.org
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

Imaging iron stores in the brain using magnetic resonance imaging

EM Haacke, NYC Cheng, MJ House, Q Liu… - Magnetic resonance …, 2005 - Elsevier
For the last century, there has been great physiological interest in brain iron and its role in
brain function and disease. It is well known that iron accumulates in the brain for people with …

Quantitative susceptibility mapping of human brain reflects spatial variation in tissue composition

W Li, B Wu, C Liu - Neuroimage, 2011 - Elsevier
Image phase from gradient echo MRI provides a unique contrast that reflects brain tissue
composition variations, such as iron and myelin distribution. Phase imaging is emerging as …

[图书][B] Pediatric neuroimaging

AJ Barkovich - 2005 - books.google.com
The thoroughly updated Fourth Edition of this acclaimed reference describes and illustrates
the full range of pediatric disorders diagnosable by modern neuroimaging. This edition …

Magnetite biomineralization in the human brain.

JL Kirschvink… - Proceedings of the …, 1992 - National Acad Sciences
Although the mineral magnetite (Fe3O4) is precipitated biochemically by bacteria, protists,
and a variety of animals, it has not been documented previously in human tissue. Using an …

High-field MRI of brain cortical substructure based on signal phase

JH Duyn, P van Gelderen, TQ Li… - Proceedings of the …, 2007 - National Acad Sciences
The ability to detect brain anatomy and pathophysiology with MRI is limited by the contrast-to-
noise ratio (CNR), which depends on the contrast mechanism used and the spatial …

Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla

F Bagnato, S Hametner, B Yao, P van Gelderen… - Brain, 2011 - academic.oup.com
Previous authors have shown that the transverse relaxivity R2* and frequency shifts that
characterize gradient echo signal decay in magnetic resonance imaging are closely …

Age-related Iron Deposition in the Basal Ganglia: Quantitative Analysis in Healthy Subjects1

D Aquino, A Bizzi, M Grisoli, B Garavaglia… - Radiology, 2009 - pubs.rsna.org
Purpose: To determine the values of iron accumulation in the basal ganglia of healthy
volunteers of different ages with R2* and raw signal intensity measurements from T1 …

MR imaging of human brain at 3.0 T: preliminary report on transverse relaxation rates and relation to estimated iron content

N Gelman, JM Gorell, PB Barker, RM Savage… - Radiology, 1999 - pubs.rsna.org
PURPOSE: To determine the transverse relaxation rates R2 and R2′ from several gray
matter regions and from frontal cortical white matter in healthy human brains in vivo and to …

T1 and T2 in the brain of healthy subjects, patients with Parkinson disease, and patients with multiple system atrophy: relation to iron content

J Vymazal, A Righini, RA Brooks, M Canesi, C Mariani… - Radiology, 1999 - pubs.rsna.org
PURPOSE: To investigate the potential of magnetic resonance imaging for identification and
quantification of brain iron in healthy subjects, patients with Parkinson disease, and patients …