Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of
death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic …

Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

As one of the most common malignant tumors worldwide, hepatocellular carcinoma (HCC) is
known for its poor prognosis due to diagnosis only in advanced stages. Nearly 50% of the …

The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

Background & Aims Liquid biopsies, or blood samples, can be analyzed to detect circulating
tumor cells (CTCs), cell-free DNA (cfDNA), and extracellular vesicles, which might identify …

Hepatocellular carcinoma (HCC) is a highly malignant disease with a poor prognosis and
high mortality due to a low early diagnosis rate, resistance to systemic treatments and …

Early detection of cancer is vital for increasing patient survivability chances. The three major
techniques used to diagnose cancers are instrumental examination, tissue biopsy, and …

Background The presence of circulating cell-free DNA from tumours in blood (ctDNA) is of
major importance to those interested in early cancer detection, as well as to those wishing to …

Hepatocellular carcinoma (HCC), with its high incidence and mortality rate, is one of the
most common malignant tumors. Despite recent development of a diagnostic and treatment …