C-reactive protein and inflammation: conformational changes affect function

Y Wu, LA Potempa, D El Kebir, JG Filep - Biological chemistry, 2015 - degruyter.com
The prototypic acute-phase reactant C-reactive protein (CRP) has long been recognized as
a useful marker and gauge of inflammation. CRP also plays an important role in host …

The role of adipose tissue and adipokines in obesity‐related inflammatory diseases

CR Balistreri, C Caruso… - Mediators of inflammation, 2010 - Wiley Online Library
Obesity is an energy‐rich condition associated with overnutrition, which impairs systemic
metabolic homeostasis and elicits stress. It also activates an inflammatory process in …

Adipose tissue and atherosclerosis: exploring the connection

G Fantuzzi, T Mazzone - Arteriosclerosis, thrombosis, and vascular …, 2007 - Am Heart Assoc
The prevalence of obesity, especially among the young, is dramatically increasing in the
United States. Obesity is associated with accelerated atherosclerosis and increased rates of …

Human C-reactive protein and the metabolic syndrome

S Devaraj, U Singh, I Jialal - Current opinion in lipidology, 2009 - journals.lww.com
Human C-reactive protein and the metabolic syndrome : Current Opinion in Lipidology Human
C-reactive protein and the metabolic syndrome : Current Opinion in Lipidology Log in or …

The evolving role of C-reactive protein in atherothrombosis

S Devaraj, U Singh, I Jialal - Clinical chemistry, 2009 - academic.oup.com
Background: Inflammation is pivotal in all phases of atherosclerosis. Among the numerous
inflammatory biomarkers, the largest amount of published data supports a role for C-reactive …

Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques

SU Eisenhardt, J Habersberger, A Murphy… - Circulation …, 2009 - Am Heart Assoc
C-reactive protein (CRP) is a predictor of cardiovascular risk. It circulates as a pentamer
(pentameric CRP) in plasma. The in vivo existence of monomeric (m) CRP has been …

Complement factor H in AMD: Bridging genetic associations and pathobiology

CB Toomey, LV Johnson, CB Rickman - Progress in retinal and eye …, 2018 - Elsevier
Abstract Age-Related Macular Degeneration (AMD) is a complex multifactorial disease
characterized in its early stages by lipoprotein accumulations in Bruch's Membrane (BrM) …

Could SCGF-beta levels be associated with inflammation markers and insulin resistance in male patients suffering from obesity-related NAFLD?

G Tarantino, V Citro, C Balsano, D Capone - Diagnostics, 2020 - mdpi.com
One of the pathologic hallmarks of obesity is macrophage infiltration of adipose tissue that
has been confirmed as source of multipotent adult stem cells. Stem cell growth factor-beta …

Intracardiac and extracardiac markers of inflammation during atrial fibrillation

GM Marcus, LM Smith, K Ordovas, MM Scheinman… - Heart rhythm, 2010 - Elsevier
BACKGROUND: A decrease in inflammation after cure of atrial arrhythmias suggests that
such arrhythmias are proinflammatory, and lower inflammatory marker levels in the coronary …

C-reactive protein polarizes human macrophages to an M1 phenotype and inhibits transformation to the M2 phenotype

S Devaraj, I Jialal - Arteriosclerosis, thrombosis, and vascular …, 2011 - Am Heart Assoc
Objective—Inflammation is pivotal in atherosclerosis. Monocyte-macrophages are crucial in
atherosclerosis. Monocytes can develop into subsets: classically (M1) or alternatively (M2) …