[HTML][HTML] Deiodinases control local cellular and systemic thyroid hormone availability
J Köhrle, C Frädrich - Free Radical Biology and Medicine, 2022 - Elsevier
Iodothyronine deiodinases (DIO) are a family of selenoproteins controlling systemic and
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …
Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases
The goal of this review is to place the exciting advances that have occurred in our
understanding of the molecular biology of the types 1, 2, and 3 (D1, D2, and D3 …
understanding of the molecular biology of the types 1, 2, and 3 (D1, D2, and D3 …
Selenium and the thyroid gland: more good news for clinicians
A Drutel, F Archambeaud, P Caron - Clinical endocrinology, 2013 - Wiley Online Library
The thyroid is the organ with the highest selenium content per gram of tissue because it
expresses specific selenoproteins. Since the discovery of myxoedematous cretinism and …
expresses specific selenoproteins. Since the discovery of myxoedematous cretinism and …
Selenium, the thyroid, and the endocrine system
J Kohrle, F Jakob, B Contempré… - Endocrine reviews, 2005 - academic.oup.com
Recent identification of new selenocysteine-containing proteins has revealed relationships
between the two trace elements selenium (Se) and iodine and the hormone network …
between the two trace elements selenium (Se) and iodine and the hormone network …
Selenium and selenoproteins in the brain and brain diseases
J Chen, MJ Berry - Journal of neurochemistry, 2003 - Wiley Online Library
Over the past three decades, selenium has been intensively investigated as an antioxidant
trace element. It is widely distributed throughout the body, but is particularly well maintained …
trace element. It is widely distributed throughout the body, but is particularly well maintained …
A theory of technophysio evolution, with some implications for forecasting population, health care costs, and pension costs
RW Fogel, DL Costa - Demography, 1997 - Springer
We argue that over the past 300 years human physiology has been undergoing profound
environmentally induced changes made possible by numerous advances in technology …
environmentally induced changes made possible by numerous advances in technology …
The role of essential trace elements in embryonic and fetal development in livestock
CE Hostetler, RL Kincaid, MA Mirando - The Veterinary Journal, 2003 - Elsevier
This review addresses the concept that essential trace minerals play a vital role in many
enzymatic and metabolic pathways that are critical for conceptus development during …
enzymatic and metabolic pathways that are critical for conceptus development during …
Defining the roles of the iodothyronine deiodinases: current concepts and challenges
DL St. Germain, VA Galton, A Hernandez - Endocrinology, 2009 - academic.oup.com
As is typical of other hormone systems, the actions of the thyroid hormones (TH) differ from
tissue to tissue depending upon a number of variables. In addition to varying expression …
tissue to tissue depending upon a number of variables. In addition to varying expression …
[HTML][HTML] Kashin–Beck osteoarthropathy in rural Tibet in relation to selenium and iodine status
R Moreno-Reyes, C Suetens, F Mathieu… - … England Journal of …, 1998 - Mass Medical Soc
Background and Methods Kashin–Beck disease is a degenerative osteoarticular disorder
that is endemic to certain areas of Tibet, where selenium deficiency is also endemic …
that is endemic to certain areas of Tibet, where selenium deficiency is also endemic …
Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis
LH Duntas, E Mantzou… - European journal of …, 2003 - academic.oup.com
Abstract Objective Selenium (Se) in the form of selenocysteine is an essential component of
the family of the detoxifying enzymes glutathione peroxidase (Gpx) and of the iodothyronine …
the family of the detoxifying enzymes glutathione peroxidase (Gpx) and of the iodothyronine …