The effects of age-related hearing loss on the brain and cognitive function

K Slade, CJ Plack, HE Nuttall - Trends in Neurosciences, 2020 - cell.com
Age-related hearing loss (ARHL) is a common problem for older adults, leading to
communication difficulties, isolation, and cognitive decline. Recently, hearing loss has been …

The search for noise-induced cochlear synaptopathy in humans: Mission impossible?

N Bramhall, EF Beach, B Epp, CG Le Prell… - Hearing research, 2019 - Elsevier
Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Hearing impairment and cognitive energy: The framework for understanding effortful listening (FUEL)

MK Pichora-Fuller, SE Kramer, MA Eckert… - Ear and …, 2016 - journals.lww.com
Abstract The Fifth Eriksholm Workshop on “Hearing Impairment and Cognitive Energy” was
convened to develop a consensus among interdisciplinary experts about what is known on …

Cochlear neural degeneration disrupts hearing in background noise by increasing auditory cortex internal noise

J Resnik, DB Polley - Neuron, 2021 - cell.com
Correlational evidence in humans suggests that selective difficulties hearing in noisy, social
settings may reflect premature auditory nerve degeneration. Here, we induced primary …

Synaptopathy in the aging cochlea: Characterizing early-neural deficits in auditory temporal envelope processing

A Parthasarathy, SG Kujawa - Journal of Neuroscience, 2018 - Soc Neuroscience
Aging listeners, even in the absence of overt hearing loss measured as changes in hearing
thresholds, often experience impairments processing temporally complex sounds such as …

On the (un) importance of working memory in speech-in-noise processing for listeners with normal hearing thresholds

C Füllgrabe, S Rosen - Frontiers in psychology, 2016 - frontiersin.org
With the advent of cognitive hearing science, increased attention has been given to
individual differences in cognitive functioning and their explanatory power in accounting for …

Supra-threshold hearing and fluctuation profiles: implications for sensorineural and hidden hearing loss

LH Carney - Journal of the Association for Research in …, 2018 - Springer
An important topic in contemporary auditory science is supra-threshold hearing. Difficulty
hearing at conversational speech levels in background noise has long been recognized as …

Olivocochlear efferents in animals and humans: from anatomy to clinical relevance

EA Lopez-Poveda - Frontiers in neurology, 2018 - frontiersin.org
Olivocochlear efferents allow the central auditory system to adjust the functioning of the
inner ear during active and passive listening. While many aspects of efferent anatomy …

The relative contribution of cochlear synaptopathy and reduced inhibition to age-related hearing impairment for people with normal audiograms

M Gómez-Álvarez, PT Johannesen… - Trends in …, 2023 - journals.sagepub.com
Older people often show auditory temporal processing deficits and speech-in-noise
intelligibility difficulties even when their audiogram is clinically normal. The causes of such …

Effects of lifetime noise exposure on the middle-age human auditory brainstem response, tinnitus and speech-in-noise intelligibility

JT Valderrama, EF Beach, I Yeend, M Sharma… - Hearing research, 2018 - Elsevier
Recent animal studies have shown that the synapses between inner hair cells and the
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most …