During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

The essential role of the brain in maintaining energy homeostasis has motivated the drive to
define the neural circuitry that integrates external and internal stimuli to enact appropriate …

This Review highlights the processing and integration performed by hindbrain nuclei,
focusing on the inputs received by nucleus tractus solitarius (NTS) neurons. These inputs …

In November 1955, Geoffrey Harris published a paper based on the Christian A Herter
Lecture he had given earlier that year at Johns Hopkins University in Baltimore, MD, USA …

Body weight is determined by a balance between food intake and energy expenditure.
Multiple neural circuits in the brain have evolved to process information about food, food …

Feeding behavior rarely occurs in direct response to metabolic deficit, yet the overwhelming
majority of research on the biology of food intake control has focused on basic metabolic …

Maintenance of body weight is fundamental to maintain one's health and to promote
longevity. Nevertheless, it appears that the global obesity epidemic is still constantly …

Motivated behaviors are often initiated in response to perturbations of homeostasis. Indeed,
animals and humans have fundamental drives to procure (appetitive behaviors) and …

Feeding is a highly complex behavior that is influenced by learned associations between
external and internal cues. The type of excessive feeding behavior contributing to obesity …

Central nervous system control of food intake involves detecting, integrating and responding
to diverse internal and external signals. For maintenance of energy homeostasis, the brain …