There has been a resurgence in gene therapy efforts that is partly fueled by the identification
and understanding of new gene delivery vectors. Adeno-associated virus (AAV) is a non …

Biomedical engineering seeks to enhance the quality of life by developing advanced
materials and technologies. Chitosan-based biomaterials have attracted significant attention …

Sodium alginate-based hydrogel was the one of the most used polymers for cell delivery.
However, the adsorption of extracellular matrix and proteins was inhibited due to the …

In this work a new density functional theory framework is developed to predict the salt-
concentration dependent swelling state of charged microgels and the local concentration of …

We have theoretically studied the uptake of a nonuniformly charged biomolecule suitable for
representing a globular protein or a drug by a charged hydrogel carrier in the presence of a …

In this work the equilibrium absorption of nanometric cosolutes (which could represent
drugs, reactants, small globular proteins and other kind of biomacromolecules) inside …

A critical hurdle in the clinical translation of nucleic acid drugs is the inefficiency in testing
formulations for therapeutic potential. Specifically, the ability to quantitatively predict gene …

Chitosan is a natural amino polysaccharide composed of multiple reactive functional groups.
It is a cationic polymer that is biodegradable, biocompatible and non-toxic. The structure of …

Abstract Poly (N-vinylcaprolactam)(PVCL) is a new temperature-responsive type of polymer
microgel with improved biocompatibility as compared to more commonly used poly (N …