[HTML][HTML] Review on recent development of quinoline for anticancer activities

M Ilakiyalakshmi, AA Napoleon - Arabian Journal of Chemistry, 2022 - Elsevier
Quinoline is an efficient scaffold for anticancer drug development as its derivatives have
shown potent results through several mechanisms like growth regulators through “apoptosis …

Recent advances in the synthesis and biomedical applications of heterocyclic NO-donors

LL Fershtat, ES Zhilin - Molecules, 2021 - mdpi.com
Nitric oxide (NO) is a key signaling molecule that acts in various physiological processes
such as cellular metabolism, vasodilation and transmission of nerve impulses. A wide …

Terpyridine copper (II) complexes as potential anticancer agents by inhibiting cell proliferation, blocking the cell cycle and inducing apoptosis in BEL-7402 cells

YQ Gu, YJ Zhong, MQ Hu, HQ Li, K Yang, Q Dong… - Dalton …, 2022 - pubs.rsc.org
Four mononuclear terpyridine complexes [Cu (H-La) Cl2]· CH3OH (1),[Cu (H-La) Cl] ClO4
(2),[Cu (H-Lb) Cl2]· CH3OH (3), and [Cu (H-Lb)(CH3OH)(DMSO)](ClO4) 2 (4) were prepared …

Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition

MM Amin, GEDA Abuo-Rahma, MSA Shaykoon… - Bioorganic …, 2023 - Elsevier
The present study established thirteen novel 8-hydroxyquinoline/chalcone hybrids 3a–m of
hopeful anticancer activity. According to NCI screening and MTT assay results, compounds …

Antitumor studies evaluation of triphenylphosphine ruthenium complexes with 5, 7-dihalo-substituted-8-quinolinoline targeting mitophagy pathways

ZF Wang, XQ Huang, RC Wu, Y Xiao… - Journal of Inorganic …, 2023 - Elsevier
Both ruthenium-containing complexes and 8-quinolinoline compounds have emerged as a
potential novel agent for malignant tumor therapy. Here, three triphenylphosphine ruthenium …

Recent progress on betulinic acid and its derivatives as antitumor agents: A mini review

Y Zhong, N Liang, LIU Yang, MS Cheng - Chinese Journal of Natural …, 2021 - Elsevier
Natural products are one of the important sources for the discovery of new drugs. Betulinic
acid (BA), a pentacyclic triterpenoid widely distributed in the plant kingdom, exhibits …

A new “off-on-off” Schiff base from quinoline and thiophene as a fluorescent sensor for sequential monitoring Ga3+ and Pd2+

M Kang, S Jiang, Y Liu, K Wei, P Liu, X Yang… - … of Photochemistry and …, 2023 - Elsevier
Abstract A Schiff base (E) N'-(2-hydroxybenzylidene)-1-(quinolin-8-yl)-5-(thiophen-2-yl)-1H-
pyrazole-3-carbohydrazide (N1) was designed and synthesized from 1-(quinolin-8-yl)-5 …

Antitumor activities for two Pt (II) complexes of tropolone and 8-hydroxyquinoline derivative

X Mo, K Chen, Z Chen, B Chu, D Liu, Y Liang… - Inorganic …, 2021 - ACS Publications
The reactions of cis-Pt (DMSO) 2Cl2 and tropolone (HL) with 8-hydroxyquinoline (HQ) or 2-
methyl-8-hydroxyquinoline (HMQ) gave [Pt (Q)(L)](1) and [Pt (MQ)(L)](2), which present …

Synthesis and biological evaluation of NO-donor containing photosensitizers to induce ferroptosis of cancer cells

X Guo, H Yu, W Shen, R Cai, Y Li, G Li, W Zhao… - Bioorganic …, 2021 - Elsevier
Photodynamic therapy (PDT) is a non-invasive treatment method for tumors by exciting
photosensitizers (PS) upon light irradiation to generate cytotoxic reactive oxygen species …

Synthesis, photophysical and photochemical properties of unsymmetrical zinc (II) phthalocyanines bearing 8-hydroxyquinoline unit

E Ahmetali, B Yıldız, EE Ahi, M Durmuş, MK Şener - Polyhedron, 2022 - Elsevier
Hydroxyquinolines (8-HQs) are very important molecules in the field of biochemistry. They
may play different roles due to their chelating ability. Especially, its interaction with different …