Living organisms routinely navigate their surroundings in search of better conditions, more
food, or to avoid predators. Typically, animals do so by integrating sensory cues from the …

Recently, organoids have emerged as revolutionizing tools with the unprecedented potential
to recreate organ-specific microanatomy in vitro. Upon their derivation from human …

During development, wound healing and cancer invasion, migrating cell clusters feature
highly protrusive leader cells at their front. Leader cells are thought to pull and direct their …

Cell migration is critical for tissue development and regeneration but requires extracellular
environments that are conducive to motion. Cells may actively generate migratory routes in …

Confined cells migrating through 3D environments are also constrained by the laws of
physics, meaning for every action there must be an equal and opposite reaction for cells to …

Many animal cells crawling on elastic substrates exhibit durotaxis and have implications in
several biological processes including tissue development, and tumor progression. Here …

Cell migration is critical for tissue development and regeneration but requires extracellular
environments that are conducive to motion. Cells may actively generate migratory routes in …

Cells interact with the extracellular matrix (ECM) mechanically to perform essential cell
function including migration, proliferation and differentiation, which are critical in …

Active matter describes systems, such as bacterial suspensions, cellular tissue or
cytoskeleton biopolymers, that extract energy from their surroundings at the single-particle …