Mitochondrial dysfunction: roles in skeletal muscle atrophy

X Chen, Y Ji, R Liu, X Zhu, K Wang, X Yang… - Journal of Translational …, 2023 - Springer
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle
health, and damage to mitochondria can lead to a series of pathophysiological changes …

The role of mitochondria in the pathophysiology and treatment of common metabolic diseases in humans

A Georgiev, C Granata… - American Journal of …, 2022 - journals.physiology.org
Common metabolic diseases such as obesity, type 2 diabetes mellitus, and nonalcoholic
fatty liver disease significantly contribute to morbidity and mortality worldwide. They are …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

Impact of high‐intensity interval training with or without l‐citrulline on physical performance, skeletal muscle, and adipose tissue in obese older adults

V Marcangeli, L Youssef, M Dulac… - Journal of cachexia …, 2022 - Wiley Online Library
Background Aging is associated with a progressive decline in skeletal muscle mass and
strength as well as an increase in adiposity. These changes may have devastating impact …

DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling

W Chen, Y Chen, R Wu, G Guo, Y Liu, B Zeng, X Liao… - BMC biology, 2022 - Springer
Background Obesity leads to a decline in the exercise capacity of skeletal muscle, thereby
reducing mobility and promoting obesity-associated health risks. Dietary intervention has …

[HTML][HTML] Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity

CA Pileggi, DP Blondin, BG Hooks, G Parmar, I Alecu… - …, 2022 - thelancet.com
Background Current paradigms for predicting weight loss in response to energy restriction
have general validity but a subset of individuals fail to respond adequately despite …

Mitochondrial dysfunction in heart diseases: Potential therapeutic effects of Panax ginseng

X Cao, F Yao, B Zhang, X Sun - Frontiers in Pharmacology, 2023 - frontiersin.org
Heart diseases have a high incidence and mortality rate, and seriously affect people's
quality of life. Mitochondria provide energy for the heart to function properly. The process of …

Melatonin Improves Skeletal Muscle Structure and Oxidative Phenotype by Regulating Mitochondrial Dynamics and Autophagy in Zücker Diabetic Fatty Rat

D Salagre, E Raya Álvarez, CM Cendan, S Aouichat… - Antioxidants, 2023 - mdpi.com
Obesity-induced skeletal muscle (SKM) inflexibility is closely linked to mitochondrial
dysfunction. The present study aimed to evaluate the effects of melatonin on the red vastus …

Clinical and biological adaptations in obese older adults following 12-weeks of high-intensity interval training or moderate-intensity continuous training

L Youssef, J Granet, V Marcangeli, M Dulac… - Healthcare, 2022 - mdpi.com
Sarcopenia and obesity are considered a double health burden. Therefore, the
implementation of effective strategies is needed to improve the quality of life of older obese …

Mitochondrial function and reactive oxygen/nitrogen species in skeletal muscle

MM Chen, Y Li, SL Deng, Y Zhao, ZX Lian… - Frontiers in Cell and …, 2022 - frontiersin.org
Skeletal muscle fibers contain a large number of mitochondria, which produce ATP through
oxidative phosphorylation (OXPHOS) and provide energy for muscle contraction. In this …