Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

Emerging biomarkers in thyroid practice and research

S Agarwal, A Bychkov, CK Jung - Cancers, 2021 - mdpi.com
Simple Summary Tumor biomarkers are molecules at genetic or protein level, or certain
evaluable characteristics. These help in perfecting patient management. Over the past …

The mechanism of DNA methylation and miRNA in breast cancer

L Ma, C Li, H Yin, J Huang, S Yu, J Zhao… - International Journal of …, 2023 - mdpi.com
Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …

Vitamin B12—Multifaceted in vivo functions and in vitro applications

K Halczuk, J Kaźmierczak-Barańska, BT Karwowski… - Nutrients, 2023 - mdpi.com
Vitamin B12 plays a key role in DNA stability. Research indicates that vitamin B12 deficiency
leads to indirect DNA damage, and vitamin B12 supplementation may reverse this effect …

[HTML][HTML] Gut microbiota changes and its potential relations with thyroid carcinoma

X Yu, W Jiang, RO Kosik, Y Song, Q Luo, T Qiao… - Journal of advanced …, 2022 - Elsevier
Introduction Emerging evidence suggests that the essence of life is the ecological balance of
the neural, endocrine, metabolic, microbial, and immune systems. Gut microbiota have been …

Epigenetic reprogramming in cancer: From diagnosis to treatment

PMS Costa, SLA Sales, DP Pinheiro… - Frontiers in cell and …, 2023 - frontiersin.org
Disruption of the epigenetic program of gene expression is a hallmark of cancer that initiates
and propagates tumorigenesis. Altered DNA methylation, histone modifications and ncRNAs …

The complex regulation of NIS expression and activity in thyroid and extrathyroidal tissues

G Riesco-Eizaguirre, P Santisteban… - Endocrine-Related …, 2021 - erc.bioscientifica.com
The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
active iodide transport into the thyroid gland and into several extrathyroidal tissues. NIS …

Environmental DNA methylation of Lymnaea stagnalis varies with age and is hypermethylated compared to tissue DNA

B Zhao, PM van Bodegom… - Molecular Ecology …, 2023 - Wiley Online Library
Environmental DNA (eDNA) approaches contributing to species identifications are quickly
becoming the new norm in biomonitoring and ecosystem assessments. Yet, information …

Molecular markers guiding thyroid cancer management

C Nylén, R Mechera, I Maréchal-Ross, V Tsang… - Cancers, 2020 - mdpi.com
The incidence of thyroid cancer is rapidly increasing, mostly due to the overdiagnosis and
overtreatment of differentiated thyroid cancer (TC). The increasing use of potent preclinical …

Epigenetic therapeutics targeting NRF2/KEAP1 signaling in cancer oxidative stress

S Zhang, S Duan, Z Xie, W Bao, B Xu… - Frontiers in …, 2022 - frontiersin.org
The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) and its negative
regulator kelch-like ECH-associated protein 1 (KEAP1) regulate various genes involved in …