The Yersinia pestis type III secretion system: expression, assembly and role in the evasion of host defenses

GV Plano, K Schesser - Immunologic research, 2013 - Springer
Yersinia pestis, the etiologic agent of plague, utilizes a type III secretion system (T3SS) to
subvert the defenses of its mammalian hosts. T3SSs are complex nanomachines that allow …

The novel Hha/YmoA family of nucleoid‐associated proteins: use of structural mimicry to modulate the activity of the H‐NS family of proteins

C Madrid, C Balsalobre, J García… - Molecular …, 2007 - Wiley Online Library
Summary The Hha/YmoA family of proteins is a group of conserved, low‐molecular‐weight
proteins involved in the regulation of gene expression. Studies performed in Escherichia …

Concerted Actions of a Thermo-labile Regulator and a Unique Intergenic RNA Thermosensor Control Yersinia Virulence

K Böhme, R Steinmann, J Kortmann… - PLoS …, 2012 - journals.plos.org
Expression of all Yersinia pathogenicity factors encoded on the virulence plasmid, including
the yop effector and the ysc type III secretion genes, is controlled by the transcriptional …

Toxin-Antitoxin Systems in Escherichia coli Influence Biofilm Formation through YjgK (TabA) and Fimbriae

Y Kim, X Wang, Q Ma, XS Zhang… - Journal of bacteriology, 2009 - Am Soc Microbiol
The roles of toxin-antitoxin (TA) systems in bacteria have been debated. Here, the role of five
TA systems in regard to biofilm development was investigated (listed as toxin/antitoxin …

The ATP‐dependent ClpXP and Lon proteases regulate expression of the Yersinia pestis type III secretion system via regulated proteolysis of YmoA, a small histone …

MW Jackson, E Silva‐Herzog… - Molecular …, 2004 - Wiley Online Library
The Yersinia pestis plasmid pCD1‐encoded type III secretion system (T3SS) is essential for
the pathogenicity of Y. pestis in mammalian hosts. T3SS‐associated genes are maximally …

Two AraC/XylS family members can independently counteract the effect of repressing sequences upstream of the hilA promoter

LM Schechter, SM Damrauer, CA Lee - Molecular microbiology, 1999 - Wiley Online Library
During infection of its hosts, Salmonella enterica serovar Typhimurium (S. typhimurium)
enters the epithelial cells of the small intestine. This process requires a number of invasion …

Protein translation and cell death: the role of rare tRNAs in biofilm formation and in activating dormant phage killer genes

R García-Contreras, XS Zhang, Y Kim, TK Wood - PloS one, 2008 - journals.plos.org
We discovered previously that the small Escherichia coli proteins Hha (hemolysin
expression modulating protein) and the adjacent, poorly-characterized YbaJ are important …

Control and benefits of CP4-57 prophage excision in Escherichia coli biofilms

X Wang, Y Kim, TK Wood - The ISME journal, 2009 - academic.oup.com
Earlier, we discovered that the global regulator, Hha, is related to cell death in biofilms and
regulates cryptic prophage genes. Here, we show that Hha induces excision of prophages …

Evidence for direct protein-protein interaction between members of the enterobacterial Hha/YmoA and H-NS families of proteins

JM Nieto, C Madrid, E Miquelay, JL Parra… - Journal of …, 2002 - Am Soc Microbiol
Escherichia coli nucleoid-associated H-NS protein interacts with the Hha protein, a member
of a new family of global modulators that also includes the YmoA protein from Yersinia …

Expression of the hemolysin operon in Escherichia coli is modulated by a nucleoid-protein complex that includes the proteins Hha and H-NS

JM Nieto, C Madrid, A Prenafeta, E Miquelay… - Molecular and General …, 2000 - Springer
Abstract The Escherichia coli protein Hha is a temperature-and osmolarity-dependent
modulator of the expression of the hemolysin operon. The Hha protein was purified and its …