Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions

WJ Neumann, LA Steiner, L Milosevic - Brain, 2023 - academic.oup.com
Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …

[HTML][HTML] Evoked potentials generated by deep brain stimulation for Parkinson's disease

J Dale, SL Schmidt, K Mitchell, DA Turner, WM Grill - Brain stimulation, 2022 - Elsevier
Background and objectives The goal of this review is to describe the general features,
mechanisms, technical recording factors, and clinical applications of brain evoked potentials …

[HTML][HTML] Local field potential activity dynamics in response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease

C Wiest, G Tinkhauser, A Pogosyan, M Bange… - Neurobiology of …, 2020 - Elsevier
Local field potentials (LFPs) may afford insight into the mechanisms of action of deep brain
stimulation (DBS) and potential feedback signals for adaptive DBS. In Parkinson's disease …

Globus pallidus internus deep brain stimulation evokes resonant neural activity in Parkinson's disease

KA Johnson, JN Cagle, JL Lopes, JK Wong… - Brain …, 2023 - academic.oup.com
Globus pallidus internus deep brain stimulation is an established therapy for patients with
medication-refractory Parkinson's disease. Clinical outcomes are highly dependent on …

Closed-loop adaptive deep brain stimulation in Parkinson's disease: procedures to achieve it and future perspectives

S Wang, G Zhu, L Shi, C Zhang, B Wu… - Journal of …, 2023 - content.iospress.com
Parkinson's disease (PD) is a neurodegenerative disease with a heavy burden on patients,
families, and society. Deep brain stimulation (DBS) can improve the symptoms of PD …

[HTML][HTML] A practical guide to invasive neurophysiology in patients with deep brain stimulation

WJ Neumann, RM Köhler, AA Kühn - Clinical Neurophysiology, 2022 - Elsevier
Deep brain stimulation (DBS) offers the unique opportunity to record human neural
population activity as multiunit activity and local field potentials (LFP) directly from the target …

[HTML][HTML] Temporally non-regular patterns of deep brain stimulation (DBS) enhance assessment of evoked potentials while maintaining motor symptom management in …

K Palopoli-Trojani, SL Schmidt, KD Baringer, TA Slotkin… - Brain stimulation, 2023 - Elsevier
Background Traditional deep brain stimulation (DBS) at fixed regular frequencies (> 100 Hz)
is effective in treating motor symptoms of Parkinson's disease (PD). Temporally non-regular …

Adaptive deep brain stimulation: Retuning Parkinson's disease

NG Pozzi, IU Isaias - Handbook of Clinical Neurology, 2022 - Elsevier
A brain-machine interface represents a promising therapeutic avenue for the treatment of
many neurologic conditions. Deep brain stimulation (DBS) is an invasive, neuro-modulatory …

Electrically evoked and spontaneous neural activity in the subthalamic nucleus under general anesthesia

NC Sinclair, HJ McDermott, WL Lee, N Acevedo… - Journal of …, 2021 - thejns.org
OBJECTIVE Deep brain stimulation (DBS) surgery is commonly performed with the patient
awake to facilitate assessments of electrode positioning. However, awake neurosurgery can …

Characterization of subthalamic nucleus deep brain stimulation evoked resonant neural activity in a large animal model: A pilot study

K Hageman, P Stypulkowski, S Stanslaski - Brain Research, 2025 - Elsevier
Recent reports have described stimulation evoked resonant neural activity (ERNA) recorded
in the subthalamic nucleus (STN) and globus pallidus internus (GPi) of patients during Deep …