Alcoholism can be defined by a compulsion to seek and take drug, loss of control in limiting
intake, and the emergence of a negative emotional state when access to the drug is …

With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Alcoholism is characterized by a compulsion to seek and ingest alcohol, loss of control over
intake, and the emergence of a negative emotional state during abstinence. We …

BACKGROUND: Corticotropin-releasing factor (CRF) and gamma-aminobutyric acid (GABA)
ergic systems in the central amygdala (CeA) are implicated in the high-anxiety, high-drinking …

Alcoholism, more generically drug addiction, can be defined as a chronically relapsing
disorder characterized by:(1) compulsion to seek and take the drug (alcohol);(2) loss of …

Rationale While stress is often proposed to play a significant role in influencing alcohol
consumption, the relationship between stress and alcohol is complex and poorly …

A complex relationship exists between alcohol-drinking behavior and stress. Alcohol has
anxiety-reducing properties and can relieve stress, while at the same time acting as a …

Binge drinking is prevalent and has serious biomedical consequences. In children,
adolescents, and young adults, it is a prominent risk factor for later development of alcohol …

Alcoholism, or alcohol use disorder, is a major public health concern that is a considerable
risk factor for morbidity and disability; therefore, effective treatments are urgently needed …

Adolescent alcohol binge drinking constitutes a major vulnerability factor to develop
alcoholism. However, mechanisms underlying this susceptibility remain unknown. We …