[HTML][HTML] Lessons learnt from COVID-19: computational strategies for facing present and future pandemics
Since its outbreak in December 2019, the COVID-19 pandemic has caused the death of
more than 6.5 million people around the world. The high transmissibility of its causative …
more than 6.5 million people around the world. The high transmissibility of its causative …
Novel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies
S Mousavi, S Zare, M Mirzaei… - Canadian Journal of …, 2022 - Wiley Online Library
Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease
outbreak, there has been an increasing interest in discovering potential therapeutic agents …
outbreak, there has been an increasing interest in discovering potential therapeutic agents …
Knowledge graph-based approaches to drug repurposing for COVID-19
J Al-Saleem, R Granet, S Ramakrishnan… - Journal of chemical …, 2021 - ACS Publications
The COVID-19 pandemic has motivated researchers all over the world in trying to find
effective drugs and therapeutics for treating this disease. To save time, much effort has …
effective drugs and therapeutics for treating this disease. To save time, much effort has …
[HTML][HTML] Regulation of m6A methylation as a new therapeutic option against COVID-19
The rapid spread of SARS-CoV-2 and the resulting pandemic has led to a spasmodic search
for approaches able to limit the diffusion of the disease. The epigenetic machinery has …
for approaches able to limit the diffusion of the disease. The epigenetic machinery has …
[HTML][HTML] HDAC inhibition as potential therapeutic strategy to restore the deregulated immune response in severe COVID-19
C Ripamonti, V Spadotto, P Pozzi… - Frontiers in …, 2022 - frontiersin.org
The COVID-19 pandemic has had a devastating impact worldwide and has been a great
challenge for the scientific community. Vaccines against SARS-CoV-2 are now efficiently …
challenge for the scientific community. Vaccines against SARS-CoV-2 are now efficiently …
Microplastics interact with SARS-CoV-2 and facilitate host cell infection
Microplastics (MP) pollution is a global issue that raises concerns about potential toxicity for
environmental and human health. The notion that SARS-CoV-2 is more stable when …
environmental and human health. The notion that SARS-CoV-2 is more stable when …
[HTML][HTML] Use of Tox21 screening data to evaluate the COVID-19 drug candidates for their potential toxic effects and related pathways
S Sakamuru, R Huang, M Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Currently, various potential therapeutic agents for coronavirus disease-2019 (COVID-19), a
global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS …
global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS …
[HTML][HTML] HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
Background Despite the significant progress achieved in understanding the pathology and
clinical management of SARS-CoV-2 infection, still pathogenic and clinical issues need to …
clinical management of SARS-CoV-2 infection, still pathogenic and clinical issues need to …
[HTML][HTML] Host microRNAs exhibit differential propensity to interact with SARS-CoV-2 and variants of concern
KJ Capistrano, J Richner, J Schwartz… - … et Biophysica Acta (BBA …, 2023 - Elsevier
A significant number of SARS-CoV-2-infected individuals naturally overcome viral infection,
suggesting the existence of a potent endogenous antiviral mechanism. As an innate defense …
suggesting the existence of a potent endogenous antiviral mechanism. As an innate defense …
HDAC inhibition as neuroprotection in COVID-19 infection
Y Sixto-López, J Correa-Basurto - Current topics in medicinal …, 2022 - ingentaconnect.com
The SARS-CoV-2 virus is responsible for COVID-19 affecting millions of humans around the
world. COVID-19 shows various clinical symptoms (fever, cough, fatigue, diarrhea, body …
world. COVID-19 shows various clinical symptoms (fever, cough, fatigue, diarrhea, body …