Sensing intracellular pathogens is a process mediated by innate immune cells that is crucial
for the induction of inflammatory processes and effective adaptive immune responses …

Toll-like receptors (TLRs) are important initiators of the immune response, both innate and
acquired. Evidence suggests that gene polymorphisms within TLRs cause malfunctions of …

Toll-like receptors (TLRs) constitute a family of receptors directly recognizing a wide
spectrum of exogenous and endogenous ligands playing the key role in realization of innate …

NOD1/CARD4 and NOD2/CARD15 are members of Nod-like receptor family. They are
located in cytosol, bind bacterial and viral ligands and play a key role in realization of innate …

The uterus is the core place for breeding new life. The balance and imbalance of uterine
microecology can directly affect or even dominate the female reproductive health. Emerging …

Growing studies revealed the association between polymorphisms in Toll-like receptor 4
(TLR4) and susceptibility to cancer, however, the results remained inconsistent. To assess …

The role played by the polymorphism located in Toll-like Receptor 9 (TLR9) as a risk factor
of cervical cancer remains elusive. Therefore, we studied the association of the TLR9− 1486 …

In recent years, there has been a significant amount of interest and vigorous studies on
mutations related to innate immunity receptor genes such as Toll-like receptors (TLR), which …

Toll-like receptors (TLRs) are critical sensors related to inflammation and tumorigenesis.
Among all subtypes, the TLR4 is a highly described transmembrane protein involved in the …

Background Emerging evidence indicated that common polymorphisms of NOD2 might
impact individual susceptibility to cancer. However, the results from published studies were …