Hirschsprung disease (HSCR) is a rare congenital intestinal disease that occurs in 1 in
5,000 live births. HSCR is characterized by the absence of ganglion cells in the myenteric …

Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the
“support” cells of the enteric nervous system, studies over the past 20 years have unveiled a …

Aim Extended total colonic aganglionosis (ETCA) represents uncommon forms of
Hirschsprung disease (HD), with aganglionosis extending into the proximal small bowel …

Background No systematic review and meta-analysis to date has examined multiple child
and parent-reported social and physical quality of life (QoL) in pediatric populations affected …

Hirschsprung's disease (HD) is a rare condition that affects newborns and is characterized
by the lack of ganglion cells in the colon. Typical symptoms include difficulty passing stool …

Abstract Background Hirschsprung-Associated Enterocolitis (HAEC) is a life-threatening and
difficult to diagnose complication of Hirschsprung Disease (HSCR). The goal of this study …

Abstract Purpose Patients with Hirschsprung disease affecting the splenic flexure or more
proximal segments present a surgical challenge. Mobilizing the transverse colon to the …

Abstract Total Colonic Hirschsprung Disease (HD) can be challenging from a diagnostic and
management standpoint and occurs in around 8% of cases of HD. Long term outcomes are …

Objective To evaluate the safety and efficacy of transanal endorectal pull-through (TEPT)
and the long-term outcomes in newborns with Hirschsprung disease (HD). Methods A total …

Abstract Purpose Hirschsprung Disease (HD) is a common congenital intestinal disorder.
While aganglionosis most commonly affects the rectosigmoid colon (rectosigmoid HD) …