[HTML][HTML] Design of therapeutic biomaterials to control inflammation
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
Dexamethasone: Therapeutic potential, risks, and future projection during COVID-19 pandemic
S Noreen, I Maqbool, A Madni - European journal of pharmacology, 2021 - Elsevier
The current outbreak of novel COVID-19 challenges the development of an efficient
treatment plan as soon as possible. Several promising treatment options stand out as …
treatment plan as soon as possible. Several promising treatment options stand out as …
[HTML][HTML] Nanoparticle-assembled bioadhesive coacervate coating with prolonged gastrointestinal retention for inflammatory bowel disease therapy
A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …
inflammatory bowel disease is to develop an orally administered drug delivery system …
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes
Transplantation of stem cell–derived β (SC-β) cells represents a promising therapy for type 1
diabetes (T1D). However, the delivery, maintenance, and retrieval of these cells remain a …
diabetes (T1D). However, the delivery, maintenance, and retrieval of these cells remain a …
Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases
Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …
Macrophage-based therapeutic strategies in regenerative medicine
KL Spiller, TJ Koh - Advanced drug delivery reviews, 2017 - Elsevier
Mounting evidence suggests that therapeutic cell and drug delivery strategies designed to
actively harness the regenerative potential of the inflammatory response have great …
actively harness the regenerative potential of the inflammatory response have great …
Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain
Ex vivo-loaded white blood cells (WBC) can transfer cargo to pathological foci in the central
nervous system (CNS). Here we tested affinity ligand driven in vivo loading of WBC in order …
nervous system (CNS). Here we tested affinity ligand driven in vivo loading of WBC in order …
[HTML][HTML] Type 1 diabetes and engineering enhanced islet transplantation
The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D)
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …
Extracellular matrix bioscaffolds as immunomodulatory biomaterials
JL Dziki, L Huleihel, ME Scarritt… - Tissue Engineering Part …, 2017 - liebertpub.com
Suppression of the recipient immune response is a common component of tissue and organ
transplantation strategies and has also been used as a method of mitigating the …
transplantation strategies and has also been used as a method of mitigating the …
Engineering immunomodulatory biomaterials for type 1 diabetes
CL Stabler, Y Li, JM Stewart… - Nature Reviews Materials, 2019 - nature.com
A cure for type 1 diabetes (T1D) would help millions of people worldwide but remains
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …