Ependymal tumors are rare CNS tumors and may occur at any age, but their proportion
among primary brain tumors is highest in children and young adults. Thus, the level of …

Abstract Purpose of Review To review state of art and relevant advances in the molecular
genetics and management of ependymomas of children and adults. Recent Findings …

PURPOSE The Children's Oncology Group trial ACNS0121 estimated event-free survival
(EFS) and overall survival for children with intracranial ependymoma treated with surgery …

Pediatric ependymomas comprise biologically distinct tumor entities with different (epi)
genetics, age distribution and localization, as well as a different prognosis. Regarding risk …

Background This report documents the clinical characteristics, molecular grouping, and
outcome of young children with ependymoma treated prospectively on a clinical trial …

Purpose To determine the long-term outcomes and the optimal dose and volume for
reirradiation of recurrent pediatric ependymoma. Methods and Materials Patients with …

Ependymoma with RELA fusion has been defined as a novel entity of the revised World
Health Organization 2016 classification of tumors of the central nervous system (CNS) …

Response criteria for paediatric intracranial ependymoma vary historically and across
different international cooperative groups. The Response Assessment in the Pediatric Neuro …

Background: Proton therapy can reduce the low and intermediate radiation dose to
uninvolved brain tissue in children with intracranial ependymomas, which may improve …

Background: The clinical management of ependymoma in childhood and adolescence is
complex and the clinicobiopathological correlates of outcome remain poorly understood …