There is now a convincing body of evidence from observational studies that the majority of
modifiable Alzheimer's disease and related dementia (ADRD) risk factors are vascular in …

Introduction: Imaging is a technique used for direct visualization of the internal structure or
distribution of biomolecules of a living system in a two-dimensional or three-dimensional …

Mass spectrometry imaging (MSI) is well-known for the non-labeling visualization of
analytes, including drugs and their metabolites in biological samples. In this study, we …

Nutrients are actively taken up by the brain via various transporters at the blood–brain
barrier (BBB). A lack of specific nutrients in the aged brain, including decreased levels of …

Female APOE4 carriers have a greater predisposition to developing Alzheimer's disease
(AD) compared to their male counterparts, which may partly be attributed to menopause. We …

Dementia is a major public health concern nowadays. Reduced levels of brain
docosahexaenoic acid (DHA) and DHA-phosphatidylcholines (DHA-PCs) in dementia …

Alzheimer's Disease (AD) presents a complex neuropathological landscape characterized
by hallmark amyloid plaques and neurofibrillary tangles, leading to progressive cognitive …

The vermilion of the human lip is a unique facial area because of certain distinguishing
features from the adjacent tissues such as the white lip (skin) and oral mucosa. However, the …

Introduction: Cancer is a heterogeneous disease that exploits various metabolic pathways to
meet the demand for increased energy and structural components. Lipids are biomolecules …

Abstract The endocannabinoid 2-arachidonoylglycerol (2AG) is an important modulator of
stress responses. Its level in the brain increases in response to stress, but region-specific …