The matrix metalloproteinases (MMP) are a family of proteolytic enzymes that degrade
multiple components of the extracellular matrix. A large body of experimental and clinical …

A compelling long-term goal of cancer biology is to understand the crucial players during
tumorigenesis in order to develop new interventions. Here, we review how the four non …

A central function of the vascular endothelium is to serve as a barrier between the blood and
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …

Mesenchymal stem cells (MSCs) are promising candidates for adult cell therapies in
regenerative medicine. To fully exert their potential, efficient homing and migration toward …

Cancer is a leading cause of death worldwide. In many cases, the treatment of the disease is
limited due to the metastasis of cells to distant locations of the body through the blood and …

Mesenchymal stem cell (MSC) transplantation, as an alternative strategy to orthotopic liver
transplantation, has been evaluated for treating end-stage liver disease. Although the …

In industrialized countries, cancer is the second leading cause of death after cardiovascular
disease. Most cancer patients die because of metastases, which consist of the self …

Radiation therapy is one of the most important treatment modalities for thoracic tumors.
Despite significant advances in radiation techniques, radiation-induced lung injury (RILI) still …

Breast cancer metastatic progression to critical secondary sites is the second leading cause
of cancer-related mortality in women. While existing therapies are highly effective in …

Various, diverse molecules contribute to the tumor microenvironment and influence invasion
and metastasis. In this review, the roles of neutrophil gelatinase-associated lipocalin (NGAL) …