Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Assembly and applications of macrocyclic-confinement-derived supramolecular organic luminescent emissions from cucurbiturils

H Nie, Z Wei, XL Ni, Y Liu - Chemical Reviews, 2022 - ACS Publications
Cucurbit [n] urils (Q [n] s or CB [n] s), as a classical of artificial organic macrocyclic hosts,
were found to have excellent advantages in the fabricating of tunable and smart organic …

Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Fluorescent small organic probes for biosensing

X Tian, LC Murfin, L Wu, SE Lewis, TD James - Chemical science, 2021 - pubs.rsc.org
Small-molecule based fluorescent probes are increasingly important for the detection and
imaging of biological signaling molecules due to their simplicity, high selectivity and …

Aggregation‐induced emission: recent advances in materials and biomedical applications

X Cai, B Liu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
The concept of aggregation‐induced emission (AIE) has opened new opportunities in many
research fields. Motivated by the unique feature of AIE fluorogens (AIEgens), during the past …

Precise molecular design for high‐performance luminogens with aggregation‐induced emission

S Xu, Y Duan, B Liu - Advanced Materials, 2020 - Wiley Online Library
Precise design of fluorescent molecules with desired properties has enabled the rapid
development of many research fields. Among the different types of optically active materials …

Preparation of near-infrared AIEgen-active fluorescent probes for mapping amyloid-β plaques in brain tissues and living mice

C Yan, J Dai, Y Yao, W Fu, H Tian, WH Zhu, Z Guo - Nature protocols, 2023 - nature.com
Fibrillar aggregates of the amyloid-β protein (Aβ) are the main component of the senile
plaques found in brains of patients with Alzheimer's disease (AD). Development of probes …

Reducing aggregation caused quenching effect through co-assembly of PAH chromophores and molecular barriers

Y Huang, J Xing, Q Gong, LC Chen, G Liu… - Nature …, 2019 - nature.com
The features of well-conjugated and planar aromatic structures make π-conjugated
luminescent materials suffer from aggregation caused quenching (ACQ) effect when used in …

Rational design of near-infrared aggregation-induced-emission-active probes: in situ mapping of amyloid-β plaques with ultrasensitivity and high-fidelity

W Fu, C Yan, Z Guo, J Zhang, H Zhang… - Journal of the …, 2019 - ACS Publications
High-fidelity mapping of amyloid-β (Aβ) plaques is critical for the early detection of
Alzheimer's disease. However, in vivo probing of Aβ plaques by commercially available …

Aggregation-induced emission: together we shine, united we soar!

J Mei, NLC Leung, RTK Kwok, JWY Lam… - Chemical …, 2015 - ACS Publications
Light is of essential importance to the universe and humankind. Light has been, and
continues to be, one of the most fundamental and indispensable elements to life and society …