Gonadotropin-inhibitory hormone (GnIH): discovery, progress and prospect

K Tsutsui, T Ubuka, GE Bentley, LJ Kriegsfeld - General and comparative …, 2012 - Elsevier
A hypothalamic neuropeptide, gonadotropin-releasing hormone (GnRH), is the primary
factor regulating gonadotropin secretion. An inhibitory hypothalamic neuropeptide for …

Seasonal control of gonadotropin-inhibitory hormone (GnIH) in birds and mammals

LJ Kriegsfeld, T Ubuka, GE Bentley, K Tsutsui - Frontiers in …, 2015 - Elsevier
Animals inhabiting temperate and boreal latitudes experience marked seasonal changes in
the quality of their environments and maximize reproductive success by phasing breeding …

Female competition and aggression: interdisciplinary perspectives

P Stockley, A Campbell - Philosophical Transactions of …, 2013 - royalsocietypublishing.org
This paper introduces a Theme Issue combining interdisciplinary perspectives in the study of
female competition and aggression. Despite a history of being largely overlooked, evidence …

Social regulation of gene expression in the hypothalamic-pituitary-gonadal axis

KP Maruska, RD Fernald - Physiology, 2011 - journals.physiology.org
Reproduction is a critically important event in every animals' life and in all vertebrates is
controlled by the brain via the hypothalamic-pituitary-gonadal (HPG) axis. In many species …

Gonadotropin-inhibitory hormone (GnIH): A new key neurohormone controlling reproductive physiology and behavior

K Tsutsui, T Ubuka - Frontiers in Neuroendocrinology, 2021 - Elsevier
The discovery of novel neurohormones is important for the advancement of
neuroendocrinology. In early 1970s, gonadotropin-releasing hormone (GnRH), a …

regulatory mechanisms of gonadotropin-inhibitory hormone (GnIH) synthesis and release in photoperiodic animals

K Tsutsui, T Ubuka, GE Bentley… - Frontiers in …, 2013 - frontiersin.org
Gonadotropin-inhibitory hormone (GnIH) is a novel hypothalamic neuropeptide that was
discovered in quail as an inhibitory factor for gonadotropin release. GnIH inhibits …

Effects of melatonin on peripheral reproductive function: regulation of testicular GnIH and testosterone

NL McGuire, K Kangas, GE Bentley - Endocrinology, 2011 - academic.oup.com
Study of seasonal reproduction has focused on the brain. Here, we show that the inhibition
of sex steroid secretion can be seasonally mediated at the level of the gonad. We investigate …

Central and peripheral neuropeptide RFRP-3: a bridge linking reproduction, nutrition, and stress response

P Singh, S Anjum, RK Srivastava, K Tsutsui… - Frontiers in …, 2022 - Elsevier
This article is an amalgamation of the current status of RFRP-3 (GnIH) in reproduction and
its association with the nutrition and stress-mediated changes in the reproductive activities …

Neural programming of seasonal physiology in birds and mammals: a modular perspective

TJ Stevenson, TA Liddle, C Stewart, CJ Marshall… - Hormones and …, 2022 - Elsevier
Most animals in the temperate zone exhibit robust seasonal rhythms in neuroendocrine,
physiological and behavioral processes. The integration of predictive and supplementary …

Advancing reproductive neuroendocrinology through research on the regulation of GnIH and on its diverse actions on reproductive physiology and behavior

K Tsutsui, T Ubuka, K Ukena - Frontiers in Neuroendocrinology, 2022 - Elsevier
The discovery of gonadotropin-inhibitory hormone (GnIH) in 2000 has led to a new research
era of reproductive neuroendocrinology because, for a long time, researchers believed that …