Classical biogenic amines (adrenaline, noradrenaline, dopamine, serotonin and histamine)
interact with specific families of G protein‐coupled receptors (GPCRs). The term 'trace …

The Genetics of Schizophrenia | PLOS Medicine Skip to main content Advertisement PLOS
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Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …

Badner and Gershon (2001) presented a technique of meta-analysis of linkage data that
could be applied to published genome scans. It combines the reported P-values of …

Prior evidence has supported the existence of multiple susceptibility genes for
schizophrenia. Multipoint linkage analysis of the 270 Irish high-density pedigrees that we …

A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide
linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected …

Abstract Analysis of global microRNA (miRNA) expression in postmortem cortical grey
matter from the superior temporal gyrus, revealed significant up-regulation of miR-181b …

Schizophrenia, schizoaffective disorder, and bipolar disorder are common psychiatric
disorders with high heritabilities and variable phenotypes. The Disrupted in Schizophrenia 1 …

Schizophrenia is a complex multifactorial brain disorder with a genetic component.
Convergent evidence has implicated oxidative stress and glutathione (GSH) deficits in the …

Research has long supported the view that the brain is immunologically privileged, in part
because normal, uninfected neurons were not thought to express major histocompatibility …