Hemorrhagic shock (HS) management is based on a timely, rapid, definitive source control
of bleeding/s and on blood loss replacement. Stopping the hemorrhage from progressing …

A shift of approach from 'clinics trying to fit physiology'to the one of 'physiology to clinics', with
interpretation of the clinical phenomena from their physiological bases to the tip of the …

Introduction In recent years the development of secondary sclerosing cholangitis in critically
ill patients (SSC-CIP) has increasingly been perceived as a separate disease entity. About …

Background: The resuscitation strategy for hemorrhagic shock remains controversial, with
the kidney being especially prone to hypoxia. Methods: The authors used a three-phase …

The clinical aspects of shock syndromes are described from their inception as compensated
physiology to a stage of decompensation. The clinical significance of hypotension, fluid …

It induces carbon dioxide generation and hypocalcemia, which are both cardiovascular
depressant factors The cardiovascular and metabolic effects of an adapted sodium …

Circulatory shock and resuscitation are associated with systemic hemodynamic changes,
which may contribute to the development of MODS (multiple organ dysfunction syndrome) …

Oxidative stress is believed to accompany reperfusion and to mediate dysfunction of the liver
after traumatic-hemorrhagic shock (THS). Recently, endoplasmic reticulum (ER) stress has …

BACKGROUND: Acute lung injury (ALI) is a complication of hemorrhagic shock (HS).
Histone deacetylase inhibitors, such as valproic acid (VPA), can improve survival after HS; …

Background Cepharanthine possesses strong anti-inflammation capacity. We sought to
clarify whether cepharanthine could mitigate pro-inflammatory cytokine production in acute …