Treatment of obesity: weight loss and bariatric surgery

BM Wolfe, E Kvach, RH Eckel - Circulation research, 2016 - Am Heart Assoc
This review focuses on the mechanisms underlying, and indications for, bariatric surgery in
the reduction of cardiovascular disease (CVD), as well as other expected benefits of this …

[HTML][HTML] Estrogen as a key regulator of energy homeostasis and metabolic health

F Mahboobifard, MH Pourgholami, M Jorjani… - Biomedicine & …, 2022 - Elsevier
Over the last two decades, it has become evident that estrogens preserve the integrity of
energy homeostasis at central and peripheral levels. Estrogen deficiency, such as that …

Non-alcoholic fatty liver disease and dyslipidemia: an update

N Katsiki, DP Mikhailidis, CS Mantzoros - Metabolism, 2016 - Elsevier
Non-alcoholic fatty liver (NAFLD) is the most common liver disease worldwide, progressing
from simple steatosis to necroinflammation and fibrosis (leading to non-alcoholic …

The pathogenesis of nonalcoholic fatty liver disease: interplay between diet, gut microbiota, and genetic background

J Yu, S Marsh, J Hu, W Feng… - … research and practice, 2016 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
world, and it comprises a spectrum of hepatic abnormalities from simple hepatic steatosis to …

Pharmacological applications of bile acids and their derivatives in the treatment of metabolic syndrome

M Ðanić, B Stanimirov, N Pavlović… - Frontiers in …, 2018 - frontiersin.org
Apart from well-known functions of bile acids in digestion and solubilization of lipophilic
nutrients and drugs in the small intestine, the emerging evidence from the past two decades …

[PDF][PDF] Hepatic natural killer T‐cell and CD8+ T‐cell signatures in mice with nonalcoholic steatohepatitis

J Bhattacharjee, M Kirby, S Softic… - Hepatology …, 2017 - Wiley Online Library
Hepatic inflammation is a key pathologic feature of nonalcoholic steatohepatitis (NASH).
Natural killer T (NKT) cells and clusters of differentiation (CD) 8+ T‐cells are known to play …

Non-alcoholic fatty liver disease phenotypes in patients with inflammatory bowel disease

A Sartini, S Gitto, M Bianchini, MC Verga… - Cell Death & …, 2018 - nature.com
Non-alcoholic fatty liver disease (NAFLD) can be detected in up to 33.6% of inflammatory
bowel disease (IBD) patients, often in absence of metabolic risk factors. Nevertheless, most …

The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome

MG Traber, GR Buettner, RS Bruno - Redox biology, 2019 - Elsevier
Metabolic syndrome (MetS) is a constellation of cardiometabolic risk factors, which together
predict increased risk of more serious chronic diseases. We propose that one consequence …

Mediterranean diet and nonalcoholic fatty liver disease: Molecular mechanisms of protection

J Godos, A Federico, M Dallio… - International journal of …, 2017 - Taylor & Francis
Nutritional habits modifications have shown an important impact in preventing and
ameliorating metabolic alterations, such as nonalcoholic fatty liver disease (NAFLD). Among …

Roles of FGFs as paracrine or endocrine signals in liver development, health, and disease

N Itoh, Y Nakayama, M Konishi - Frontiers in cell and developmental …, 2016 - frontiersin.org
The liver plays important roles in multiple processes including metabolism, the immune
system, and detoxification and also has a unique capacity for regeneration. FGFs are growth …