Role of neuroinflammation in neurodegeneration development
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
Signaling pathways in Parkinson's disease: molecular mechanisms and therapeutic interventions
X Dong-Chen, C Yong, X Yang, ST Chen-Yu… - Signal transduction and …, 2023 - nature.com
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …
Neuroinflammation in Parkinson's disease–putative pathomechanisms and targets for disease-modification
A Grotemeyer, RL McFleder, J Wu… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) is a progressive and debilitating chronic disease that affects more
than six million people worldwide, with rising prevalence. The hallmarks of PD are motor …
than six million people worldwide, with rising prevalence. The hallmarks of PD are motor …
The systemic immune response in Parkinson's disease: Focus on the peripheral immune component
J Lauritsen, M Romero-Ramos - Trends in neurosciences, 2023 - cell.com
During Parkinson's disease (PD), both the central nervous system (CNS) and peripheral
nervous system (PNS) are affected. In parallel, innate immune cells respond early to …
nervous system (PNS) are affected. In parallel, innate immune cells respond early to …
DAT and TH expression marks human Parkinson's disease in peripheral immune cells
Parkinson's disease (PD) is marked by a loss of dopamine neurons, decreased dopamine
transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation …
transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation …
Role of α-synuclein in microglia: Autophagy and phagocytosis balance neuroinflammation in Parkinson's disease
QK Lv, KX Tao, XB Wang, XY Yao, MZ Pang… - Inflammation …, 2023 - Springer
Background Parkinson's disease (PD) is the second most common neurodegenerative
disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation …
disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation …
The immune system in Parkinson's disease: what we know so far
Parkinson's disease is characterized neuropathologically by the degeneration of
dopaminergic neurons in the ventral midbrain, the accumulation of α-synuclein (α-syn) …
dopaminergic neurons in the ventral midbrain, the accumulation of α-synuclein (α-syn) …
Regulation of pain perception by microbiota in Parkinson disease
Pain perception involves current stimulation in peripheral nociceptive nerves and the
subsequent stimulation of postsynaptic excitatory neurons in the spinal cord. Importantly, in …
subsequent stimulation of postsynaptic excitatory neurons in the spinal cord. Importantly, in …
[HTML][HTML] Impact of sex on neuroimmune contributions to Parkinson's disease
M Bourque, M Morissette, D Soulet, T Di Paolo - Brain Research Bulletin, 2023 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease. Inflammation has been observed in both the idiopathic and familial …
Alzheimer's disease. Inflammation has been observed in both the idiopathic and familial …
[HTML][HTML] The role of antiviral CD8+ T cells in cognitive impairment
KL Reagin, KE Funk - Current opinion in neurobiology, 2022 - Elsevier
The impact of the immune system on the etiopathogenesis of neurodegenerative diseases,
including Alzheimer's disease, is a rapidly growing area of investigation. Evidence from …
including Alzheimer's disease, is a rapidly growing area of investigation. Evidence from …