Obesity is a chronic disease associated with increased risk of obesity-related complications
and mortality. Our better understanding of the weight regulation mechanisms and the role of …

Importance Obesity affects approximately 19% of women and 14% of men worldwide and is
associated with increased morbidity. Antiobesity medications (AOMs) modify biological …

Background Obstructive sleep apnea is characterized by disordered breathing during sleep
and is associated with major cardiovascular complications; excess adiposity is an etiologic …

Importance Despite its demonstrated benefits in improving cardiovascular risk profiles, the
association of tirzepatide with mortality and cardiovascular and kidney outcomes compared …

For more than a century, physicians have searched for ways to pharmacologically reduce
excess body fat. The tide has finally turned with recent advances in biochemically …

Importance Obesity has become a global public health concern and China has the largest
number of affected people worldwide. Objective To assess the efficacy and safety of …

Introduction Glucagon-like peptide 1 receptor agonists (GLP-1) elicit substantial reductions
in glycemia and body weight in people with type 2 diabetes (T2D) and obesity, but existing …

Metabolic and bariatric surgeries have been shown to be the most effective strategy to
induce and maintain significant weight loss for people living with severe obesity. However …

Background Obesity has reached epidemic proportions, with> 40% of the US population
affected. Although traditionally managed by lifestyle modification, and less frequently by …

The rising phenomenon of obesity, a major risk factor for the development and progression
of type 2 diabetes, is a complex and multifaceted issue that requires a comprehensive and …