Inclusion complex with cyclodextrins enhances the bioavailability of flavonoid compounds: A systematic review

B dos Santos Lima, S Shanmugam… - Phytochemistry …, 2019 - Springer
Flavonoids are the polyphenolic compounds widely found in plants, which possess several
pharmacological activities such as, antioxidant, antinociceptive, anti-inflammatory, antiviral …

Recent advances on chiral mobile phase additives: a critical review

Y Li, XN Jin, Y Cheng, XF Ma, Y Wang - Journal of Analysis and Testing, 2022 - Springer
Chirality is one of the fundamental attributes of nature, which exists in different or even
completely opposite metabolic, toxicological and pharmacological properties in organisms …

Quality by design in the chiral separation strategy for the determination of enantiomeric impurities: development of a capillary electrophoresis method based on dual …

S Orlandini, B Pasquini, M Del Bubba, S Pinzauti… - … of Chromatography A, 2015 - Elsevier
Quality by design (QbD) concepts, in accordance with International Conference on
Harmonisation Pharmaceutical Development guideline Q8 (R2), represent an innovative …

Enantioseparation of basic drugs by reverse phase high‐performance liquid chromatography system using carboxymethyl‐β‐cyclodextrin as chiral mobile phase …

Q Ao, H Zhao, T Tong, Y Peng, Z He - Chirality, 2022 - Wiley Online Library
A rapid and efficient method was developed for enantioseparation of basic drugs, using
carboxymethyl‐β‐cyclodextrin (CM‐β‐CD) as chiral mobile phase additive, rather than …

Preparation of polar group derivative β-cyclodextrin bonded hydride silica chiral stationary phases and their chromatography separation performances

B Zhao, L Li, Y Wang, Z Zhou - Chinese Chemical Letters, 2019 - Elsevier
Three novel β-cyclodextrin compounds derived with piperidine which is flexible, l-proline
containing a chiral center, ionic liquid with 3, 5-diamino-1, 2, 4-triazole as the cation were …

Preparation and chromatographic evaluation of a chiral stationary phase based on carboxymethyl-β-cyclodextrin for high-performance liquid chromatography

M Zhou, Y Long, Y Zhi, X Xu - Chinese Chemical Letters, 2018 - Elsevier
A chiral stationary phase (CSP) was prepared by chemically bonding carboxymethyl-β-
cyclodextrin (CM-β-CD) onto 3-aminopropyl silica gel through amidation reaction in water …

Enantioseparation of five racemic N‐alkyl drugs by reverse phase HPLC using sulfobutylether‐β‐cyclodextrin as a chiral mobile phase additive

B Chen, H You, L Fang, T Lin, P Xu… - Journal of Separation …, 2022 - Wiley Online Library
Analytical enantioseparations of five N‐alkyl drugs, fluoxetine hydrochloride, labetalol,
venlafaxine hydrochloride, trans‐paroxol, and atropine sulfate, were investigated by reverse …

An economic, accessible and stable sulphated cyclodextrin polymer as selector for efficiently separating chiral drugs in HPLC

Y Nan, P Zheng, X Yuan, X Xu, X Zhang, Y Li - Microchemical Journal, 2024 - Elsevier
In this study, sulfopropyl ether β-cyclodextrin polymer (SPE-β-CDP) with simple synthesis
steps using cheap reagents was large-scalely prepared. Characterization results showed …

Enantioseparation of nine indanone and tetralone derivatives by HPLC using carboxymethyl‐β‐cyclodextrin as the mobile phase additive

X Hu, X Guo, S Sun, B Zhu, J Yu, X Guo - Chirality, 2017 - Wiley Online Library
High‐performance liquid chromatography (HPLC) is a powerful method in the area of chiral
separation. In this study, a method of HPLC using carboxymethyl‐β‐cyclodextrin (CM‐β‐CD) …

Enantioseparation of N‐methyl duloxetine, duloxetine, and fluoxetine by countercurrent chromatography using anionic β‐cyclodextrin as chiral selector

W Sun, B Chen, H You, L Fang, J Qian… - Journal of Separation …, 2022 - Wiley Online Library
Two anionic β‐cyclodextrins as chiral selectors were successfully applied in the
enantioseparation of N‐methyl duloxetine, duloxetine, and fluoxetine by countercurrent …