Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via
a balance between bone formation by osteoblasts and resorption by osteoclasts. These …

This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Our sense of touch emerges from an array of mechanosensory structures residing within the
fabric of our skin. These tactile end organ structures convert innocuous forces acting on the …

PIEZO channels respond to piconewton-scale forces to mediate critical physiological and
pathophysiological processes,,,–. Detergent-solubilized PIEZO channels form bowl-shaped …

Human-sensitive mechanosensation depends on ionic currents controlled by skin
mechanoreceptors. Inspired by the sensory behavior of skin, we investigate zwitterionic …

Electronic skin (e‐skin) technology is an exciting frontier to drive the next generation of
wearable electronics owing to its high level of wearability, enabling high accuracy to harvest …

Mechanotransduction is a fundamental ability that allows living organisms to receive and
respond to physical signals from both the external and internal environments. The …

Understanding cell types and mechanisms of dental growth is essential for reconstruction
and engineering of teeth. Therefore, we investigated cellular composition of growing and …

Nerve injury leads to chronic pain and exaggerated sensitivity to gentle touch (allodynia) as
well as a loss of sensation in the areas in which injured and non-injured nerves come …

The mechanosensitive Piezo channels function as key eukaryotic mechanotransducers.
However, their structures and mechanogating mechanisms remain unknown. Here we …