[PDF][PDF] Vascular endothelial growth factor (VEGF)-key factor in normal and pathological angiogenesis

CS Melincovici, AB Boşca, S Şuşman… - Rom J Morphol …, 2018 - rjme.ro
Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …

Lymphatic vessels in cancer

LC Dieterich, C Tacconi, L Ducoli… - Physiological …, 2022 - journals.physiology.org
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph
nodes that are present in almost every tissue of the human body, acts as an essential …

CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2

R Amraei, W Yin, MA Napoleon, EL Suder… - ACS Central …, 2021 - ACS Publications
As the COVID-19 pandemic continues to spread, investigating the processes underlying the
interactions between SARS-CoV-2 and its hosts is of high importance. Here, we report the …

Vascular endothelial growth factor signaling in development and disease

S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …

Lymphangiogenesis and lymphatic vessel remodelling in cancer

SA Stacker, SP Williams, T Karnezis, R Shayan… - Nature Reviews …, 2014 - nature.com
The generation of new lymphatic vessels through lymphangiogenesis and the remodelling
of existing lymphatics are thought to be important steps in cancer metastasis. The past …

Lymphatic system in cardiovascular medicine

A Aspelund, MR Robciuc, S Karaman… - Circulation …, 2016 - Am Heart Assoc
The mammalian circulatory system comprises both the cardiovascular system and the
lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …

[HTML][HTML] A systems biology approach identifies FUT8 as a driver of melanoma metastasis

P Agrawal, B Fontanals-Cirera, E Sokolova, S Jacob… - Cancer cell, 2017 - cell.com
Association of aberrant glycosylation with melanoma progression is based mainly on
analyses of cell lines. Here we present a systems-based study of glycomic changes and …

Signal transduction by vascular endothelial growth factor receptors

S Koch, S Tugues, X Li, L Gualandi… - Biochemical …, 2011 - portlandpress.com
VEGFs (vascular endothelial growth factors) control vascular development during
embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There …

Molecular regulation of angiogenesis and lymphangiogenesis

RH Adams, K Alitalo - Nature reviews Molecular cell biology, 2007 - nature.com
Blood vessels and lymphatic vessels form extensive networks that are essential for the
transport of fluids, gases, macromolecules and cells within the large and complex bodies of …

[HTML][HTML] Lymphangiogenesis: molecular mechanisms and future promise

T Tammela, K Alitalo - Cell, 2010 - cell.com
The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of
pathological processes including tissue inflammation and tumor dissemination but is …