Prebiotic chemistry aims to explain how the biochemistry of life as we know it came to be.
Most efforts in this area have focused on provisioning compounds of importance to life by …

Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

How and where did life on Earth originate? To date, various environments have been
proposed as plausible sites for the origin of life. However, discussions have focused on a …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

Theories about the origin of life require chemical pathways that allow formation of life's key
building blocks under prebiotically plausible conditions. Complex molecules like RNA must …

The RNA World concept posits that there was a period of time in primitive Earth's history—
about 4 billion years ago—when the primary living substance was RNA or something …

The general notion of an “RNA world” is that, in the early development of life on the Earth,
genetic continuity was assured by the replication of RNA, and RNA molecules were the chief …

Either to sustain autotrophy, or as a prelude to heterotrophy, organic synthesis from an
environmentally available C1 feedstock molecule is crucial to the origin of life. Recent …

The chemistry of abiotic nucleotide synthesis of RNA and DNA in the context of their
prebiotic origins on early earth is a continuing challenge. How did (or how can) the …

Boron is an essential mineral that plays an important role in several biological processes.
Boron is required for growth of plants, animals, and humans. There are increasing …